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1. Those that make it clear from the start that there is a 'caste system', with the management at the top, the permanent employees next,

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

with the contractors being the 'untouchables'.

2. Those that say "I could never work just for money the way you guys do". Most companies

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

and managers forget that contractors need to be motivated too. They don't work for money on a day-to-day basis. They take the job for mo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ney, just like the permanent employees. Managers are usually the biggest de-motivators of contractors, especially when they say things li

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

e, "You shouldn't need to be motivated when you earn the money you do".

3. Those that keep a beady eye on the people that work for them,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to make sure that everyone is working every minute of every day. It increases the stress on workers who already have deadlines. Everyone

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

needs to have a mental break every so often to be fully effective, so why should they have to hide this from their dumb employer?

4. Th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

se that ban contractors from any benefits, e.g. using the Sports & Social Club facilities, the Staff Canteen, or attending the Christmas

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Party. If they allow them to go to the Christmas Party, they charge them the full whack, making it clear that they resent the money that

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

they are paying the contractors, when in fact they are paying no more or no less than market rates.

5. The serial sackers - those that g

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

t a buzz from sacking a contractor every so often to prove their toughness. It has to be for a reasonably minor offence such as reading a

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

newspaper five minutes after lunchtime ends, and it must be done 'on the spot' to encourage the others. The contractor is escorted off t

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

he site in order for the serial sacker to obtain full satisfaction, so that he doesn't need to do again it for a while.

6. Those that co

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

mplain loudly about contractors leaving at five o'clock. He or she is, of course, unwilling to pay any overtime. Everybody wants somethin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

for nothing. You never meet any who let you leave early regularly when there is not enough work to do, and who still pay you your full r

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ate for it. If they don't think it is worth paying for your time, they can't consider it that important, and you shouldn't either.

7. Th

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ose that tell you that your rate, as with that of the other contractors, will be cut by 10% from Monday, otherwise you will be out of a j

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

b. You could just imagine what would happen in boom times if contractors said that they would be, en masse, leaving their crucial project

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

on Monday unless their rates were increased by 10% all round. You could imagine the weeping and gnashing of teeth if that happened. Even

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

worse are the employers who have a second bite of the cherry and cut rates again by 10% just a few months after they previously cut them

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Prototypes are a working example of a new design. And before moving towards creating multiple copies of this prototype, the company will generally use the prototype to test its viability and quality.

Advertising in the paper works for many people in business. The astute merchant understands the newspaper’s weaknesses and works to avoid them whenever possible.

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