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Before conducting an interview, the interviewer must understand the fundamentals of behavior as it relates to the act of lying. During the interview, the interviewer must be concerned with whether or not

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a potential employee is telling the truth and accurately describing his or her background. A candidate may be able to lie successfully because the interviewer is not in tune with the prospective employe

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e’s non-verbal clues that indicate deception. Becoming aware of the manifestations of dishonesty is a vital skill in becoming a great interviewer.

Interpreting non-verbal behavior is the least understood

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

element of communication. Between 55% and 65% of all communication between two people is conveyed through body language, while 30% to 40% of this same communication is carried in the tone of voice. Thi

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s leaves less than 10% to the spoken word. Therefore, it should be absolutely clear that an interviewer must be concerned with a candidate’s non-verbal responses. These silent clues may provide more inf

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ormation than the applicant's own answers.

The subconscious and conscious mind act separately. Lying and simultaneously attempting to control the many different signals, emotions and other physical beha

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

viors indicative of dishonesty is almost impossible for the unpracticed conscious mind. (Most people have a hard enough time keeping their stories straight!) A candidate will experience some level of st

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ress during an interview, which will create minor amounts of incongruent non-verbal behaviors. The signals we are concerned with tend to manifest themselves when the candidate subconsciously feels the hi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ghest levels of stress, stemming from the fear that their lies may be detected. This increased stress induces telltale behaviors. The candidate's behaviors are the result of an unconscious attempt to pr

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

otect or distance themselves from the source of stress, which in most cases is the interviewer and his or her questions.

Non-verbal behavior reveals itself in body positioning, gestures, eye contact, and

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

facial expressions. Evaluating verbal responses involves awareness of tone, volume, and speed of speech. Other tactics include evaluating a candidate’s attitude, use of various delay techniques (abnorma

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

l pauses between a question and the applicant's answer) and listening for verbal slips. While these clues can be indicative of a candidate’s dishonesty, they cannot be used individually and separately in

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

making a good appraisal of a candidate’s responses. First, suspected behavior must be compared to a “norm” for the candidate. And secondly, the suspected behavior must be evaluated in context with the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

discussion.

Establishing a candidate’s “norm” simply means determining how this person responds to questions that he or she does not find threatening. For example, answering questions regarding one’s na

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

me, date of birth, or social security number should not be stressful, assuming the candidate is not attempting to conceal their identity. Other questions regarding their drive to the interview, the weath

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

er and other current events will help an interviewer begin to establish how the candidate uses verbal and non-verbal behavior in non-threatening communication. During these neutral questions the intervie

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

wer, concerned with establishing a “norm,” should be evaluating the following:

• The amount of eye contact with the interviewer

• Body position, in relation to the interviewer

• How a candidate uses

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

his hands or gestures while speaking

• Other body movements

• Facial expression

• How quickly the candidate responds to the interviewer’s questions

• The candidate’s tone and volume of their voic

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e

After spending time relaxing the candidate, building rapport, and establishing a “norm,” the interviewer should then make the transition into asking well-crafted "integrity questions" regarding informa

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

tion contained in the employment application and resume and monitoring the applicant for subtle deviations in behavior which may indicate stress related to a specific question and the corresponding answer

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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