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When its time to leave the company you currently work for you should always act in a professional manner. Remember you may need them for a reference and also you nev

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

er know when you may cross paths with them again.

Just imagine if you had let your emotions run away with you and you had told the boss exactly what you thought onl

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

y to find later that they knew your new employers or worse still eventually ended up working with or in your new company.

So best thing to do is always keep things

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

n a nice basis. Keep calm, never express any anger. The following are some points you may wish to note:-

You should:-

• Stay professional
• Advise your emplo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

yers face to face and give them your resignation letter
• Remember you may come into contact with them at a later stage
• Chose your references carefully

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and let them know your intentions and why you think you’re suitable for the new job.
• Avoid any insults or aggressive conduct

You should never:-

• Hand your

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

notice in when you’re angry
• Think that you have to give any reason at all why you want to leave – it’s your choice
• Vent your frustration at them tel

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ling them of all the bad things you don’t like about their company.

If the issue that made you want to think about leaving related to financial reasons you should t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ll them so. It’s possible they may want to think about increasing your package rather than losing you to another company. Sometimes a letter of resignation can trigg

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

er this but you need to think carefully you don’t want to be back in the same position in another year’s time and you would also be messing about the company that ha

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

made you the offer and that might scupper any chance of you getting back in with that employer in the future.

When you resign it’s a good idea to do so after you h

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ave obtained another position. Not only would that give you less of the obvious financial strains that leaving a job without one to go to would produce but you would

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

also be better placed. It’s often a fact that employers often prefer to employ those that are already in employment rather than those that are not. So try to get yo

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r ideal new job secured first. A number of online job sites can help you find what you need in this direction. The online job site www.redgoldfish.co.uk is extremely

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

useful for finding new jobs and can help you secure your ideal job using the free services the site offers. Even if you dont have a current CV the site will help yo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

build one free of charge so that you can present your details to new employers in the best possible light. It’s nice to be in a position of power when resigning kno

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

wing that you have an alternative job lined up, so you should take advantage of the free job sites available on the internet as one of the ways to put you in a posit

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ion of strength when you make that resignation decision.

Despite the fact that it’s a good idea to find alternative employment first prior to resigning many employe

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s do resign without a job to go to, often it might be because they want to take a gap from work to reassess what they want to do next or just to take a holiday to th

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ink things over. What ever your reasons or choices for wanting to resign you should always think carefully about it and always go about it in a professional manner

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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