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Bar codes are a series of vertical bars of different width, in which digits from zero to nine are

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

represented in a dissimilar pattern of bars forming a code that can be read only by a laser scan

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ner. It is representation of machine-readable information on a visual surface. These codes are fo

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

und on consumer products and are specially used for inventory control.

There are different types

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

of bar codes such as one-dimensional bar codes, which use the width of the bar code to encode ju

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

st a product or account number. The second type of bar codes includes DataMatrix, MaxiCode, and P

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

DF417, which are scanned horizontally as well as vertically, and contain more data than the first

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

type. These two-dimensional bar codes are used for high-speed sorting and small parts. These bar

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

codes help to identify packages, mails, customer accounts, and similar items. A computer helps in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

decoding the bar codes by optically scanning the printed pattern. By reading bar codes on produc

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ts, record information about the item such as its price and quantity sold can be obtained from th

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e database.

The pattern of bar codes has evolved over time. Initially they were only a set of ve

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

rtical lines. Today, they are available in a pattern of concentric circles, dots, or hidden image

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s. In modern times, the high rate of theft makes it necessary for installing bar codes on almost

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ll products. All objects present in a mass merchandiser a grocery store and department store have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

bar codes present on them. Bar codes are also used by airlines to track down the passenger's lug

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

gage and to reduce the chances of loss and theft. Rental car companies use bar codes on their car

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

bumpers to help them identify and keep track of the vehicle. The bar code on each car is unique,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

which facilitates easy location of the car in case it gets stolen.

Bar codes have become indisp

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ensable in today's world. They are extensively used as a safety measure in all areas of operation

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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