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Machine shops are manufacturing units that produce specific machinery. They can be eithe

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

r small scale or big companies. A person or a company already involved in this field is

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ometimes interested in taking over another machine shop that is for sale. The shop on sa

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e could be so because of its non-performance, lack of productivity, or labor problem. It

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

could also be due to a personal problem of the owner.

There are certain machine shops f

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

r sale that are high gross profit businesses. They generally have no competition, since

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hey serve a sector of the high tech industry such as medical, scientific instrumentation

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

or high-end electronic requirements. They have a varied customer base with no single cli

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

nt contributing for more than 15%. Many of these companies for sale have ISO certificati

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n as a mark of quality control. They also boast of a good employee base with tried and t

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sted procedures and tremendous growth potential.

It is important for the person buying

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

he shop to prepare himself for each stage of the buying process. The buyers should be ab

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

olutely certain about the type of business that is right for them and then search for th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

se shops. It is important to negotiate all the details to ensure a deal that is worthwhi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e for both the buyer and the seller. The maintenance and after sale service aspect of th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

company is also important and the prospective buyer should seek detailed information ab

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ut it. The buyer should ascertain whether the previous owner has any intention to stay o

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

till the buyer settles in.

It is imperative on part of the buyer to investigate every

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

spect of the business for sale such as the industry, customers, suppliers, finance and c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mpetition, to understand everything about the business before signing on the dotted line

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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