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Switching from petroleum to synthetic industrial lubricants is one of the most effective ways to cut manufacturi

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ng and production costs. Synthetic industrial lubricants have a proven track record of lowering energy costs as

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

well as enhancing and prolonging equipment life. According to some studies, switching from petroleum to syntheti

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

c lubricants can cut production costs by 2%-8%, and there are some companies that are getting even better result

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

.

The benefits of using synthetics as industrial lubricants include:

- lower operating temperatures for machin

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ery

- longer equipment life

- lower energy costs

- reduced waste

- higher lubricant purity

In one specific

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

case study, a cements manufacturer switched one air compressor from the mineral oil that they usually used for l

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ubricating its parts to a synthetic industrial lubricant. The results were monitored by an independent monitorin

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

agency in order to get a totally unbiased reading of the test. In the end, the company found that the use of th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e right lubricant reduced energy costs by 16%. As a result, the company decided to switch all of its air compres

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sors over to using synthetic lubricants. The additional benefits included:

- reduced energy consumption

- annu

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

al energy savings of ?33,500

- longer running times between oil drains, saving more money by reducing lubricant

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

costs

- reduced waste oil amounts

Based on those figures, the study suggests that using the right industrial l

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ubricants can help reduce energy inefficiency by about 33%. In other words, if a machine is operating at 85% eff

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

iciency, its inefficiency rating is 15%. Switching the lubricant used in the machine can raise its efficiency le

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

vel to 90% efficiency – a 1/3 decrease in the inefficiency rating, from 15% to 10%.

Of course, you’ll only see

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

his benefit if you actually keep up on the maintenance of your machines. If you create and maintain a maintenanc

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e program that includes regularly scheduled viscosity checks for your lubricant and replacement BEFORE equipment

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

starts to wear from friction, you’ll be saving even more energy and money. And in these days with fuel prices r

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ising and our global environment showing the signs of the strain we put on it, every little bit of savings helps

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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