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Insiders all agree: stand up pouches have revolutionized the packaging industry. Their unique construction has opened the door for manufacturers

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

of all types of products to take advantage of the branding and merchandising benefits stand up pouches offer. In addition, their unique ability t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

be customized makes them an ideal solution to many packaging needs.

A stand up pouch is a laminated film bag, usually constructed from differen

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

plastics or a blend of plastic and aluminum foil. They are ideal for makers of foodstuffs like sugar or salt, or even for personal care items li

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ke soap, because they eliminate a lot of the excess packaging that molded plastics and cardboard containers typically create.

Available in a var

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ety of shapes and sizes, one of the most important things for manufacturers to consider before employing the use of stand up pouches is how they

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ant consumers to access the product. The options are plenty; whether it is via a zipper or a sticker, the method you choose is completely depende

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nt upon the type of product contained within the pouch. Here is a brief summary of the different access methods to help you determine which is be

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

t for you:

SLIDER

Stand up pouches that close by a sliding zipper are probably the most convenient method for consumers to use. They do not hav

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

to use scissors or knives to open the package, and can easily be used by those with arthritis or other health problems that hinder manual dexter

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ty. The slider also guarantees a complete sealing of the zipper, so consumers will not have to rely on secondary storage methods to keep the prod

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

uct fresh.

HOODED SLIDER

This is the slider method taken to the next level. For those consumers who worry about product tampering, the hooded s

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ider provides an extra layer of protection, giving them the peace of mind they need. In this method, a visible tear away seal above the zipper cl

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

arly shows whether or not the package has been opened. There is also a seal within the slider itself that provides even more security from tamper

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ing.

PRESS-TO-CLOSE (PTC) ZIPPER

In this method, the zipper seal on the stand up pouch is closed when the consumer presses the male and female

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ides of the zipper together, creating a locked seal. It is an extremely economical method to use on a stand up pouch, but not necessarily the mos

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

user-friendly.

STICKERS

Stickers can be used for a variety of different applications on stand up pouches. Should you wish, suppliers of stand

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

up pouches can place a registered sticker on your package that gives you an extra opportunity to brand your product or to give the consumer addit

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

onal information. They can also be used as a recloseable option.

With the variety of access options available with stand up pouches, there is un

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

oubtedly a method that will work best for you. All you have to ask yourself is: how does each access method stand up to the demands of my product

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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This article tells us the prime differences between online and offline financial trading and discusses some benefits and pitfalls of each method.

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