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For manufacturers of consumer goods, and especially for the retailers who sell them, one of the largest sources of

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

profit loss stems from theft. The National Association for Shoplifting Prevention (NASP) estimates that U.S. reta

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

lers lose over $10 billion annually from shoplifting alone, a figure that translates to $25 million every single d

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

y!

However, in recent years the packaging industry has begun to introduce new methods that have helped deter thef

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

. Through the use of clamshell and blister packaging, manufacturers have been able to help retailers in their ques

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

to minimize theft.

Made from a variety of different types of plastic, such as PVC, Polystyrene, Polyethylene PET

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

or Recycled Polyethylene RPET, clamshell and blister packages are sealed around the edges of the package, making i

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t extremely difficult for thieves to steal a product by taking it out of its package while still in the store. Thi

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

saves retailers the money they would normally spend replacing a product, and saves consumers the money they would

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

have to spend in price increases to make up for the cost of product theft.

Clamshells and blisters also offer a h

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

gh level of rigidity, which makes them impact resistant. In addition, they can be readily customized to fit to the

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

specific contours of a particular product, making them ideal for manufacturers of delicate items that could be dam

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ged while undergoing the shaking and bumping that takes place during distribution of the product. The plastic from

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

which the clamshells and blisters are made can also be treated with anti-static and static dissipative materials,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

making them ideal for electronic products that require extra protection from electrical charges.

Marketing profes

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ionals also like clamshell and blister packaging because they can be made using extremely transparent plastic mate

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ials, so the product is easily viewed by potential consumers. Clamshells and blisters can be made to sit or stand

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n a shelf, or even hang in a display, which gives retail merchandisers more options when designing eye-popping, at

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ention-grabbing displays.

Any which way you look at it, clamshell and blister packaging helps manufacturers, reta

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

lers, and consumers alike. The bottom line is this: clamshell and blister packaging can help save your bottom line

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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