Digg It - Business

Making wood and water come together to create high quality production-graded paper is the business of most paper

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

mills. Paper mills taking water directly from rivers or wells, have to worry about sludge and other impurities

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

hich contaminate their processing equipment and compromise the quality of paper. This problem can be solved by i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

nstalling some state-of-the-art self-cleaning filters with 150-micron stainless steel cartridges to trap any deb

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

is that may be dredged up from the river.The HC self-cleaning filter is the right and convenient choice for its

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ow maintenance requirements and reasonable cost. The HC self-cleaning filter, all stainless steel construction,

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

is a filter that operates on water pressure alone.

Principle of operation: while water goes in

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o the filter cartridge, the filtered water exits leaving the dirt in the cartridge chamber. As dirt particles co

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lect on the cartridge, the line pressure at the filter outlet drops. As the quantity of these dust particles inc

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

reases, the pressure reaches a preset differential – the cleaning cycle begins Within a few seconds and without

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nterrupting the main flow the carrier shaft starts revolving the scraper blades, made of stainless steel (also P

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

FE and PTFE+SST according to the application) which clean the cartridge, removing the dirt from the inside. The

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ball valve is attached and the dirt comes out of the filter. The above cycle is programmable by the user. Becaus

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

of the automatic flushing, there is no plant downtime for routine filter cleaning, which translates to greater

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

roductivity for the plant.The HC self-cleaning filter not only saves labor costs. It also saves energy and chemi

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

cal costs due to the lower volume of water used in the back flushing process. The benefits of HC self-cleaning f

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lter may be thus summed up in: "Reduction in water usage, ease of maintenance, simple design, reasonable cost ,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nd improved efficiency on cleaning". HC self-cleaning filters are produced by TECSI S.r.l., an Italy-ba

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

sed company that specializes in industrial and irrigation filtration systems. TECSI range of self-clean

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ng filters offers a wide choice of capacities and materials, to fulfill the most various needs.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Tags

Links

Digg It - Papermaking Application: How Self-Cleaning Filters Can Help!

Related Articles: