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The technology isn’t a new one though. For years composites or sandwich panels have been used in the manufacture of both civilian and military aircraft and more recently used in racing vehicles, ship building and even specialized architecture. A typical Boeing civil airliner may be comprised of up to 5-15

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

% composite panel, although recently Boeing announced that the new 7E7 would be composed of up to 50% composite, making it ultra light weight while maintaining optimum durability.

The success of composite technology in the aviation field has made it attractive to other industries seeking to apply the ben

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

efits. One of the more significant for the trucking profession is that core composite materials measure in much lighter than steel and aluminium with an average weight savings of up to 40% over steel and 20% over aluminium.

At present, composite technology can be applied to body panels and accessories, f

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ront-end panels, floor, engine block, cargo liners, vehicle chassis, bumper beams, fuel tank supports, heat-resistant parts such as inlet manifold, cooling modules, and oil pan… Heavy wood or metal decking on trailers may be replaced with sandwich panel to further shed pounds and leverage added payload an

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

d longer trailer deck life. Diversity in the materials used and in the manufacturing process enables composite panels to be fashioned into flat or curved forms that possess one of the highest strength to weight ratios of any structural material available on the market.

Replacing just a class 8 sleeper bo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

x with custom manufactured composite panel technology can reduce overall vehicle weight by up to 850 pounds, effectively decreasing gross weight and fluid resistance while increasing payload.

In addition to lightweight composition, the sound dampening and insulation properties create a quiet environment

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

inside the sleeper; corrosion resistance, and overall durability are also high on the ratings scale.

The panels are formed when two materials are combined to create a stronger substance than either of the two base materials on their own. The panels themselves are heated and thermo fused to the matrix or

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ore; the matrix binds together the fibres of the stronger material, called the reinforcement. The reinforcement can be engineered from glass fibre, aramid and carbon whereas the matrix can comprise polyester resins, vinyl ester resins, or epoxy resins, as well as many light fibre materials. The separation

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

of the skins by this low-density core increases the moment of inertia of the beam or panel with very little increase in weight, producing a highly efficient structure. Throughout the extensive use of high strength adhesives, composite panels are precisely joined together providing superior enhancements i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

n relationship to conventional riveting or welding processes. Staying ahead from conventional practices allows the industry to perceive tangible savings linked to lower direct labour cost, tooling, equipment but mainly eliminating expensive rust and corrosion issues or claims.

Essentially the strength of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the composite panel depends on its overall size, the surface material used, and the density of the cells inside it, the thicker the core, the higher the stiffness and strength of the panel. By careful selection of reinforcement, matrix and production process, manufacturers are able to produce industry sp

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ecific composite panels. Composites designed for heavy commercial applications such as aircraft manufacturing, aerospace industry, oil exploration and military markets utilize high-strength, continuous fibres such as polyurethane foam or other dynamic materials to ensure a rigid panel that can withstand w

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ear and tear due to loading stresses or mechanical strain. For low strength and stiffness or low stress applications such as automotive, marine, and industrial parts, a matrix composed of non-continuous fibres like paper or card can be used ensuring optimum strength-to-weight ration for the particular app

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

lication.

By varying composition and thickness, compressive and tensile strength and resistance to deflection keep damage from rocks and debris as well as stress in loading and unloading to a minimum. If damage does occur, panel replacement is relatively easy and affordable and can be repaired at most au

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

o-body repair facilities.

A generic composite panel is generally described as:

Some overall benefits are:

Lighter (but strong) materials provide lower fuel consumption
Can be customized to many specific applications
Relatively fast implementation times
Noise dampening pr

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

operties block out ambient noise from outside the interior

Resistant to harmful chemicals and heat

They last longer

Minimized structural noise

From a manufacturing or engineering standpoint:

When shock and impact loads are an issue the honeycomb cell size can be a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

djusted to achieve different compression strengths.

Working prototypes using laminated panels and sandwich panels can be developed to within 4-6 weeks of inception. The manufacturing processes is geared to maximum efficiency and optimum implementation times

The insulation value (R value)

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

can range from 2.5 to up to 6 depending on the thickness of the panels. Specific customer requirements can be achieved through the use of special honeycomb cores and facings

The range of materials used to manufacture panels to specification makes it an attractive option for truck manufacturers

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Versatility of design in body and door panels, hoods, roof panels, bonnets, and spoilers allow for drastic reduction in fluid drag and rolling resistance. Ongoing research and development is providing continuous advancements in composite performance and expanding the range of applications. The trans

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

portation industry is welcoming composite technology which may soon replace wood and metal as the material of choice.

Edison Reis, B.Sc. Eng.
Engineering & Quality Assurance Manager
Canadian Commercial Vehicles Corp.
www.ccvbc.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

Anyone considering entering into the carpet cleaning business has a dream of making money through contracting others to clean. The problem is many people end up wasting their expertise working for someone else because they couldn't get enough customers to keep their own business running. Times have changed and people looking for carpet cleaners turn to the internet as their first point of call. Knowing how to advertise your carpet cleaning business over the internet is more than half your battle.

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Several considerations for an effective customer service program as part of core strategy to serve customers well.

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