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Every carwash owner is looking for a system that is fully automatic and robotic for th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

eir tunnel carwash so that they do not have to do any pre-prep washing. If you ever g

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

o to a fully robotic carwash you might notice before the car goes in there is someone

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

there with a little pressure washer, a brush and a soap mitt getting the car ready to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

o through the tunnel.

The first time you see this you think yourself why is that pers

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

on there? Shouldn’t the automatic carwash be good enough to clean the car without any

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

human labor? Well that is the dig really; the truth is no, most of them can't. It is

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

unfortunate that robotic carwash cleaning equipment costs so much and does not fully c

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lean the car properly. If the carwash owners do not pre-prep the car then there will

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

be customer complaints.

Of course if they do prep the car prior to wash it slows the

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

peed, cuts down the volume of cars that can be washed in the day and changes the consi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

stency of each car washed due to the human element. All this is true of course howeve

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

r, not all cars are created equally. Consider if you will that every car has differen

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

t bodylines and the robotic carwash system may not be able to get to everything.

Thos

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hard to get to spots can be cleaned in advance and pre-prepped prior to entering the

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

tunnel carwash. There is somewhat of a debate that goes on in the industry, as to whe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ther carwash owners should pre-prepped the cars.

But in the end if the car is not cle

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n enough the customer is not happy and therefore they will not return and you will eve

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ntually go into business for not enough customers or get a bad reputation and the comp

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

etition will end up smoking you in the market place. Please consider all this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Deciding on the right career is one of the toughest challenges faced by a high school graduate. Often, young graduates are not able to decide whether to continue with their studies or to settle down with a job. In the post World War II period, taking up a job was the obvious choice because of opportunities in several flourishing industries and their requirement for young graduates. However, due to technological advances and high paced work styles, the current job market has altered considerably. Excessive competition, high salary expectations and geographical constraints are some of the factors that have contributed to the difficulty in finding jobs, especially those that would suit a high school graduate. New age employers and industries look for candidates for specialized jobs, which makes it almost compulsory for all graduates to have a professional degree or a specialized diploma.

Sometimes management force employees to compromise their intergrity. If owners really knew what went on in their big business policies.

Andy Weekes emailed me with this story: I thought you would like to see the following, received by a friend from an online CD retailer in the US, after his order was dispatched.

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