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Have you ever seen the dolphin show? It was spectacular! The dolphins were able to perform the stunt instructed by

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

their trainers. They can jump through the burning frame, dance in unison and carry the trainers around the pool. Th

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

dolphins are very intelligent indeed and can communicate with human and thus able to perform many incredible stunt

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

giving proper training.

However, did you notice every time the dolphins finished a stunt requested by the tra

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ners, they were given a small fish as a reward? Imagine this scenario, the trainers instructed the dolphin to perfo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

m some incredible stunts, after which they told the dolphins they would be given their rewards at the end of the da

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

. What would be the dolphins felt? I believe the next time they will not perform as well as they expected to be.

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easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r>How do you reward your employees today? Did you ask them to achieve high target (incredible stunt) but told them

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

hat they will get their incentives at the end of the year. Though the idea of giving the incentive at the end of th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

year is a norm in most industries, it can be a de-motivating factor to the employee. For some, they felt that they

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

have been chasing carrot without knowing whether at the end of the year they will get their incentives; especially

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

or those organizations which will only announced incentives or bonuses when the company overall performance is maki

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

g good returns. This is actually punishing the high performers for the under productivity of the low performers, It

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

usually create discontentment.

Why not from today, learn something from the dolphins trainers; reward your emp

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

oyees instantaneously so that they feel that they have been take care off and will perform even better for the next

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

stunt (target) you set for them. Why wait until end of year to reward the high performers, your immediate reward ne

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

d not be huge but it will motivate them to a greater height.

One real estate agency that I knew had adopt this

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

philosophy to reward their sales staff, every time they conclude a deal and payment received, the sales staff will

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

et his commission immediately. They do not have to wait for the end of the month. While many estate agencies are fi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ding it difficult to find leads on buyers, they never run out of leads.

Learn something from the dolphin today

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Companies that design, assemble, produce, and test electronic components and assemblies for original equipment manufacturers are known as electronic manufacturing services.

Are you sick of paying for advertising or oblivious that your marketing is sick?

In today’s competitive business, companies must lower their operating costs and increase productivity but many companies are reluctant to upgrade with new tools and technologies. They fail to realize is that having aging software will result in higher operating costs, excess inventory – meaning a decrease in bottom line profits.

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