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Fitting is one of the important criteria for consumers in their buying decision. Every garment manufacturer have target segment with certain demographic characteristics, defining

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

consumer profile. For getting the best fit and size dimensions, manufacturer spends big chunks of money. Best range of sizing can be a key success factor for manufacturers. To i

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

mplement this many companies are using advanced technologies and strategies to device sizing systems and sizing categories.

Following are the issues central to the sizing proble

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

m:

Collecting data on age, body structure and ethnicity: Data can be colleted by sample survey method that can represent the population as a whole. Selection of sample is very c

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rucial as these are bases to arrive at conclusions. Various statistical tools can help in getting range and variation of sizes found in people. Now-a-days companies are better eq

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uipped with technologies such as automated measurement and 3D body scanning. These tools facilitate more effective and affordable data collection for garment manufacturing compan

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ies.

Demographic Data: Data such as age, income, education, lifestyle and socio-economic status are also important factors affecting sizing, but unfortunately very few manufactu

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rers work on such data.

Idea about fittings: Patternmakers, graders, designers and customers themselves- all have different perceptions about the best fit. Designer has his idea

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

about match between size of outfit and body dimension that will give the perfect look. Patternmakers seek to maintain this look over a range of bodies. Customers have their pers

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

onal preferences and perceptions about which size gives a better look and feel of comfort. The effectiveness of sizing system is highly dependent on skills of patternmakers and g

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

raders in identifying, defining and manufacturing the type of fit appropriate for the target market. Some of the tools and strategies to facilitate this are target body scanner,

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

market surveys, wear testing, and virtual fit assessment.

Style, design, and material as well as production methods used: Each style defines the relationship between body and si

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ze. Each new style of outfit that is produced is aimed to fit range of bodies in an acceptable manner. Some style like a baggy one can fit many bodies with marginal difference. T

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

he design of a garment also influences fitting, especially when design is complex.

Materials with stretching characteristics can fit a wider range of body.

Various stages in pr

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

oduction significantly affect the final specifications of a garment. Wrong selection of fabrics, shrinkage, defects in machinery, errors in marker making and cutting, and inaccur

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ate sewing can lead to distort the expected size. For such problems production management need can make use SQC (Statistical Quality Control) Techniques and emphasize on quality

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

control and consistency.

Size labels: Communication of clothing sizes is also one of the crucial issues. Many times it is seen that consumers get confused with the sizes. They a

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

re not able correlate the numbers with body measurement, so they prefer taking trials of various sizes of same item. The reason behind this is non standardization of label sizes

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

among manufacturers. To get rid of this problem, manufacturers are using terms such as slim, classic, relaxed fit. This problem more complex for women’s clothing then men’s. Wome

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

n’s clothing is generally labeled using size numbers that do not relate to any particular dimension of the body or garment. Men's sizing normally corresponds to body measurements

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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