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A mutual fund could set a benchmark as a target for the performance. For such a fund, one that is 100% focused on the stock-

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

market, the benchmark could be a stock-market index, like the Dow Jones. For individual portfolios that carry more than stoc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s only but include currencies and bonds, it is more difficult to define an appropriate benchmark.

And that is exactly the p

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

roblem with benchmarking as a performance management instrument in organisations. How are you to measure a performance if ev

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ry company is unique and wants to deviate from the standard?

And that is exactly the problem with organisations. How are yo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

u to measure a performance if every company is unique? Benchmarking is done to compare activities with the objective to impr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ve these. So how do we translate the financial adagio, “If we beat the index, we have done well,” into an organizational cou

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

nterpart?

Benchmarking you company against peers is sheer impossible; a small difference in focus, product offering will ma

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

e an overall comparison useless.

So you should step down to get more focus and therefore a reliable or credible benchmark.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

For instance you could visit three sales teams and use the one with the best results as a benchmark. The other two will try

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

o improve their sales using the benchmark as the best practice. Yet the three sales organisations differ slightly. One sales

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

team is focused on active clients, the other on clients that you offer additional services. A benchmark would do more harm

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

n this area, because it will flatten the differences your company introduced to increase overall sales. Instead of having th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ree teams you just as well may go back to having only one.

The problem of a benchmark is also present for mutual funds mana

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ers because they can deviate less from the market that they might want to. But an organization could do this. If you have se

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

t a strategy they only way to implement this is by setting the benchmark according to the strategic rules. That is not by ob

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

erving others, but by benchmarking against your own profile.

For the market sake you could add some market condition indica

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

tors that level the (benchmark) outcome with the market situation; these should be in line: a positive market outlook should

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

increase the level of the benchmark.

(As for the Hollywood divorces, I haven’t check the level being more or less than aver

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

age, but I assume that the quality of live in Hollywood is neither better not worse, but just “different”.)

© 2006 Hans Boo

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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