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Watson Wyatt Worldwide, a national business group with a focus on health, recently took a survey among 275 emplo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

yers to find out the key issues affecting employee productivity.

Their findings show the stress was identified

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

y 72% of the employers as a key issue relative to productivity.

Stress has been building in the workplace as em

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

loyers find it increasingly necessary to have more work done by fewer employees. The result has been that employ

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

es have been asked to take on additional responsibilities, work longer hours, cross train with other departments

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

and do more multitasking.

After stress in the survey, 59% said a key issue affecting employee productivity wer

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

personal and family issues. Personal and family issues include such items as day care, family illnesses, marita

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

l stress, financial troubles, and other personal issues.

Following close behind in third place, 58% cited chron

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

c medical conditions. This issue barely squeaked ahead of unscheduled absences.

Stress becomes an issue because

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

so many people are unable to deal with stress. A certain amount of stress is necessary and an important part of

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

aily life. However people often will ignore this routine stress until it amplifies and starts to take a toll on

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

heir life.

What you can do

As an employer, you are able to do many things to help reduce stress in the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

workplace. Here are just some suggestions:

==> increase the lighting, particularly natural lighting, it has man

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

workplaces as possible

==> do not overcrowd your employees, provide as much space as possiblespread live plant

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s throughout the workplace as they create calmness

==> align an individual employees ability to handle stress w

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

th the normal stress of each position -- the use of employee of assessments is vital in this endeavor

==> enco

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rage employees to cut absenteeism through programs that reward attendance or unused sick payprovide stress manag

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ment classes for your employees -- companies like Max Impact offers viable stress management classes on-site or

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nline

The bottom line with stress is that an employer can have a huge impact on the stress levels of the employ

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

es.

Through proper training and proper site management, stress can be significantly reduced.

-----------------

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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