estselling fieldbook "Learning to Fly ? Practical knowledge management from leading and learning organisations", written by
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
tp://www.chriscollison.com>Chris Collison and Geoff Parcell.
Example 1) In BP, well known for its knowledge-sharing culture, the senior
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
leadership developed a habit of reinforcing "learning from others" when they visited operational sites.
Imagine the scene: the Director or Sen
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
ior VP arrives, and is given the usual tour of the site. They sit down with the management team and review the performance of the business against a
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
set of stated KPIs. One of these KPIs is currently not being met. What happens when they identify this issue?
"Have you thought abo
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ut approach X? Addressed performance issue Y? Changed widget Z?"
..will generate one set of behaviours.
"Who else have you spoken with at
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
other sites who might have a similar issue?"
..will drive a very different set of behaviours.
This is the route that BP has chosen to take; se
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
nior management visits are opportunities to reinforce the value of learning from others, rather than opportunities to underline their seniority by pr
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
oviding "the answer".
Example 2) When the senior directors from energy and essential services company, Centrica, met to discuss how to impr
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
ove knowledge sharing in the company, they agreed a set of practical "leadership challenges" for senior managers across the organisation:
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
How can I personally demonstrate that "asking for help" is a sign of strength rather than weakness?
When encountering a business problem, t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
how can I reinforce the importance of learning from others - rather than simply providing an answer?
When reviewing a project or investmentping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
proposal, have I challenged to ensure that it brings to bear knowledge from other projects?
How do I react when someone fails - is it purey and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ly a loss to the business, or is it an investment in their education?
Do my team see failure as something to learn from, or something to co.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
ver up?
These kind of questions and challenges bring to life the notion of knowledge management in a tangible, practical manner.
What w
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
ould work in your organisation?
If you could issue five challenges to your senior team, what would you choose?
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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
