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    The following list cannot - and doesn't intend to - be a complete list because the spectrum of products and suppliers is just too broad, however, it can as
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    sist in serving 'OUR clients' better and avoid to be exchangeable as a supplier.

    Yet we must not forget that nowadays the competition is just an 'email/a
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    mouse click' away - even if it is on the other end of the world. The clients will choose him, if he is in a position to SERVE THEIR NEEDS better than us -
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    just around the corner.

    * 1. General

    Our client does not live in a vacuum, but has to satisfy in-turn the needs of HIS CLIENTS - otherwi
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    se again the competition will entice them away.

    What more stands to reason that WE care already for the needs of HIS clients, giving him a better basis of
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    discussion ? ... possibly even a mutual basis for further developments of solutions needes in the future ??

    * 2. Personal

    What is the
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    advantage of CRM and other 'good aids' - it is nothing more ! - if we forget the finally deciding factor: 'Man/Our client' ? No PC has an as complex brain
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    like man - not to talk even about our feelings - and the client is open for any help which we can offer -, however, we have to take the time to 'understan
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    d' him or in other words we have to build a 'personal relationship' (not just CRM).

    A higher price is no more really decisive if the other factors like se
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    rvice, trust in us, openness, honesty and more.

    For regular contacts or for information purposes for new colleagues, however, CRM can be perfectly used.

    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    * 3. The market/OUR clients are decisive

    We have to realize, again and again, that we will never sell something only due to a good price
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    - yet, if all the other factors are comparable, the price will be paramount.

    We sell something that satisfies the needs of our clients, i. e. the executio
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    n which HE wants (even if yellow instead of red) resp. which is to his advantage - which, as said above, will bring either himself or HIS clients an advant
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    age with regard to speed, reliability, profit, and so forth.

    Let's begin to develop our very personal 'finger print' by

    * - being different - h
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    owsoever, depending on the product/market/market segment and

    - serve our clients requests better

    - have in mind a perfect flow of information

    -
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    keep our promises

    - serve him acc. to HIS preferred ways of distribution (which should not be crate a problem nowadays with the Internet and other possib
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    le ways of distribution)

    thus

    * - simply put HIM into the absolute foreground of our activities !!

    ... in doing so 'marketing' will be helpful - in ANY
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    market of the world.

    * Addendum:

    * Quotation: Reinhold W?rth (who became a billionaire during few decades) in 'S?ddeutsche Zeitung, Nr. 41, 19/20.2.20
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    05' (well-known and big newspaper in Germany):

    "The salesman should communicate directly with the client, not via the box (= PC ) - by PCs man will degrad
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ed to a supernumerary".

    This should be taken into consideration just generally with regard to his success - and I have never seen a PC acquiring clients.


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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