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A new client of mine bought a 54-year-old company and told me that his first objective was to give the company a long overdue face-lift including a new logo. We sat down to talk about what he wanted, and though he wa

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s relatively open to ideas, I received strict orders to avoid the yellow and orange combination used in the company's current logo. While we were on the discussion of color, I brought out a Pantone swatch book to foc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s our efforts. My client was curious about how designers like myself went about choosing color.

While getting a design degree, I took several semesters of color theory. I learned to look at color in many different w

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ays, how colors react to each other, the relative nature of color, the emotive quality of color, how a prism breaks light into a rainbow, and about additive and subtractive color theory. I told my client that most de

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

igners develop their own sense of color after a lot of practice. When my client left, I realized that the way I chose color was really not based on scientific theory or anything I learned in college. The truth is tha

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

I never learned anything as valuable as the rules dictated by the basic box of Crayola crayons.

First of all, there really are only eight colors. Pantone comes out with newer, bigger swatch books every few years, b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ut the reality is that there are still the eight basic colors we learned about in first grade: red, orange, yellow, green, blue, purple, brown and black. According to Roy G. Biv (the acronym for rainbow colors), indi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

o is supposedly part of the rainbow, but let's face it: indigo is blue. Pantone gives the illusion of more, thousands more, but if you cut any little swatch out of it's horizontal home in the narrow vertical Pantone

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

an-book and looked at it independently, you would recognize it as one of the basic 8 colors. It may be lighter or darker, but it's still one of the basic eight. While my second-grade teacher was teaching my classmate

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

s and me about Roy G. Biv, we were educating each other on color theory. Practicing our rainbows with a box of Crayolas taught us all we needed to know about color. Following is a list of things I think about before

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

hoosing color.

Brown is the color of poop
Never use brown and yellow together.
No one likes orange.
Together, dark blue and black look like a bruise.
Green and red mea

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Christmas.

Pink is girly unless it's for bubble gum.

Black and yellow always look like a bumblebee.

Pastels are babyish.

Red means love and stop.

Green means go

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

and money and spring.

Dark purple is for royalty.

Dark green, dark blue and dark red are for golf-playing fathers on business trips.

Everyone likes the ocean, jeans and the sky so ev

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ryone likes blue.

Red and blue on white paper is patriotic.

If you use a yellow crayon and you don't press hard enough you can't really see it.

Paper is white so white crayons are poi

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

tless.

Orange and black is for Halloween.

Black is good for outlines, details, letters and licorice.

If you use a red crayon and you don't press hard enough you get pink.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

urple is good for boys or girls and anyone in between

If you're only allowed to use one crayon, pick a dark one--you can get a lot of colors if you press hard in some spots and lightly in others.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

l>

There you have it. I personally love orange and I think that black and dark blue can be a very sophisticated combination, but if you're not comfortable choosing color, you can refer to the list for support. Panto

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e colors have replaced crayons in my life, but I find myself thinking back to this list often. For example, I know that if I use yellow in a project, I can't use subtle screens of yellow because they won't show up. O

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

r if I'm creating a bold design with red and another color, I avoid using screens of red because light pink is anything but bold. It helps to understand that there is no white ink in standard printing in the same way

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

to a second-grader, there is no point to a white crayon.

I hope this list, culled from my years of professional experience, will help you steer clear of mistakes and make you feel a little more educated about color

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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