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When I was a small kid, I remember going to my Uncle Barry's house and be amazed at his paintings. His paintings looked so real, it was hard to disting

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

uish them from photographs. I thought he was on the road to being famous.

A few years later my uncle's wife passed away suddenly and he literally lost

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

everything he owned. At the time, he owned the Gold's Gym in Huntington Beach, California. As it turned out, his wife had all the business sense and he

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

just helped the customers. When she passed away, he sold the gym and was scammed by the new owners and never received anything beyond his down payment.

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Anyway, I thought he would be fine because his paintings were so good, I figured he could always make a great living with his paintings. To this day,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

my uncle has not sold more than 2 or 3 of his paintings despite the quality of his work and creativity of his mind. He has 2 great kids, but he has spe

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t the majority of his time with them living off various welfare programs.

A few weeks ago, I was in Barcelona, Spain and had a chance to visit the Pic

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

asso museum. I really enjoyed seeing Picasso's work but couldn't help thinking that my uncle's work was better than any of the paintings I saw at the m

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

seum. It was an absolute shame and waste of his talent that his artwork never sold. In the art world, along with most other things, you can have the gr

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

atest product ever created and unless you can market it properly, no one will ever know about it or take advantage of what you offer.

I can relate to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

his story because I have spent the majority of my adult life thinking of businesses to start. When I was in Desert Storm, I almost scooped out oil that

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Saddam had dumped into the Persian Gulf and tried to sell it as kind of a war souvenir but I was in the Persian Gulf on didn't have a way to get it to

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

the U.S. In 1992, I almost started an on line dating website but my wife talked me out it thinking no one would ever use the Internet to find a date. I

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

almost started a company that sold branded bracelets around this same time frame but didn't have the start-up money. I did start a business selling ice

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

cream from a kiosk at a mall in Mankato, Minnesota and another business helping people get money back from overpaid taxes but they both failed.

My on

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y point here is that I have spent a lot of thought trying to start the perfect business and until recently, none of them were all that perfect. Now, I

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ave finally started the perfect business and I am having the same problems my uncle had and still has I have something that is absolutely perfect and n

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

eed help getting the word out. The business is growing steadily I have signed up about 300 members to this kind of pseudo MLM shopping site but if peop

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e really understood how it worked, I should eventually have millions of members.

I do get a chuckle off some of the things that people do to become su

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

cessful many people are making a ton of money off ideas that aren't that great but for some reason their idea takes off.

Let me know if you can relate

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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