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When it comes time to print your brand identity materials, there's one overarching question for you to consider — whether to print the resulting materials on a digital printer or traditional press. There are many differences between the two processes, some of which are outlined below.

Digital Printing

Less expensive — Digit

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

al printing is a direct-to-paper printing process. As a result, it often runs about one-half of the cost of press printing.

Lose color accuracy — Digital printing is a four-color printing process. Four colors — cyan, magenta, yellow, and black — are printed in tiny dots that when visually mixed together, create various

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

colors. This, in addition to the different set-ups and settings on the machines from press-to-press, batch-to-batch and printer-to- printer, can produce a wide range of different color results. You can never be certain what you'll get.

Lose color range — Four-color printing has limitations on the brightness, saturati

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

on, and range of colors available — when mixing colors in this way. To produce bright reds, oranges, blues, and purples, especially, press printing is a better choice.

Cost of proofing — Proofing is one way to produce accurate color. Proofing can be costly, especially when compared to the overall cost of the job. But,

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

since the proof is created on the same equipment that the final job is printed on, it is often quite accurate.

Can be faster — Since no pre-press work or press setup is needed, running your job on a digital press can be faster, depending on how many jobs the printer has in the queue before yours. Some printers can ev

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

en offer same-day service. Three days is a standard turnaround time for many of the web-based digital printing companies.

Limited paper choice — Digital presses can only accommodate a limited paper thickness, and many digital printing companies only offer smooth, white papers. Thus, if a thick business card is importan

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t to you, then digital printing is not your right choice.

Limited finishing choices — Foil stamping, metallic inks, and embossing services are usually not offered by digital printing houses. Some digital printers also do not offer die-cutting or special folding services.

Limited choice of material sizes, styles, and f

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ormats — Digital printers will offer a very specific "menu" or range of products. If you want to create innovative marketing materials, such as the brochure-style business cards that we create at elf design, then digital printing is not a choice for your project. Large formats are also not available with many digital

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

printers, as the largest paper size they can accommodate is 11" x 17".

Press Printing

More costly — The difference in costs is mainly due to setup costs. For press printing, films must be produced, and plates may have to be produced as well, which are additional items that add to the overall cost. Additional time is i

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

nvolved in setting up and aligning the press, as well as washing the press. Also, there are more overruns from traditional printing, since you cannot program in a specific number of pages to be printed as you can with a digital printer. Most printers consider overruns to be billable, or they add an additional cost for

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

that into the initial estimate. Jobs done on a press will typically run about twice the cost of digital printing.

Excellent color accuracy — The Pantone Matching System (PMS) offers great color accuracy. Pantone colors are mixed to precise, pre-set specifications, which are printed each year in their color matching g

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

uides. You can consult these books to see exactly what the final color will look like in advance. It's a lot like going to the paint store and specifying colors for your home on the paint chips they offer — you know what you'll get. So, if color accuracy is important to you, then press printing may be the best choice.

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Brighter colors are available — Since the Pantone colors are mixed using inks, they can be created to be much brighter and more intense. So, if lively colors are important to your brand image, then press printing may be the way to go.

Cost of proofing — For four-color press jobs, proofing is often not too expensive w

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hen compared to the overall cost of the job. However, it can be inaccurate, depending on the type of proof run and the type of press on which your final job will be printed.

For two- or three- color jobs printed using the Pantone system, complete color proofing is often not available. However, samples of the colors are

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

available in the Pantone books. And, inexpensive laser prints or inkjet prints can be created to view the positioning of the elements of the page. With a little imagination, you can visualize how the final job will look.

Press printing can take longer than digital — There are several additional steps involved in pre

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ss printing, which are taken care of using direct-to-press, digital technology. Films and plates must be made, the press set up, run the job and then tune us needed for drying. Then cutting, folding, and other finishing must take place.

Types of paper — Choose from an entire rainbow of paper colors — fire-engine red

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

to deep blue, sunflower yellow to pitch black. There is also a wide range of thicknesses and textures from which to choose, including specialty papers, such as vellum and metallic papers. If you are considering using nontraditional paper your card or materials, press printing is the best way to go.

Fine line screens ar

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e available — The result of this is that even under close inspection, the color will look smooth and seamless. It will also appear brighter and more intense.

Wide range of finishing techniques — All finishing options are possible with press printing. Metallic inks can be run through the press as easily as can a nonmeta

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

llic ink. Embossing, die cutting, and foil stamping can be done in traditional printing houses. You can create materials that really stand out using these techniques.

Innovative formats, shapes, and sizes are possible — Traditional press printing can accommodate a wide range of paper sizes and can result in innovative

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

and creative finished projects. This is largely due to the "have-it-your-way" range of options, where you can specify special sizes and finishing techniques.

We hope that the above primer on the pros and cons of both digital printing and press printing helps you to decide which you will choose to produce your materials

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Digg It - Digital Printing vs. Press Printing - A Comparison Guide

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