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New Delhi, March 29: In an encouraging spate of retail outlets opening in the National

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

Capital Region in the last six months, Reliance Fresh can claim hands down that it is

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

on top and rising. The sales have exceeded all estimates with average sale by a store

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

being of the order of Rs five lakhs, while the company had estimated the same to be

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

around Rs Two lakhs.The footfalls are also high being 4,000 per day.

The 100th store

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

in the retail chain is to be opened soon–, the question being debated is whether Pune

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

can beat Delhi and breast the 100th outlet landmark. If so Delhi will have the honour

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

of being the 101st shop.

Without wanting to be identified, sources within the Relian

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ce group of companies say the company has so far opened 96 Reliance Fresh stores, spre

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ad over a carpet area of 2,50,000 sq ft in 96 outlets in different parts of the countr

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

y .

Delhi has 24 of the 96 shops in the country today. and accounts for thirty per ce

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nt of the total sale.

The company claims there has been overwhelming response to Reli

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ance retail in the period under review. Looking at the very encouraging response from

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

the public and the buyers, there are plans to commission more city distribution center

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s and city processing centers that will further strengthen the supply chain.

Also, ba

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ck end sourcing has been strengthened so that the demand is not left unattended or not

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

met. The effort also is to step up quality controls and checks. and help the existing

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

vendors by providing them quality products. Additionally, it is stated that the mot

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

her company of Reliance Fresh, Reliance Industries Ltd is pitted to start in the Natio

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

nal Capital Region a hyper market that will sell electronics goods as part of project.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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