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The use of steel containers by the freight shipping industry is having a significant affect on tra

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nsportation costs and practices.

Steel containers are fast becoming the preferred option for ship

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ents of cargo around the world. As they can be stacked easily they have helped to reduce freight s

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hipping costs. Furthermore the products that they contain are more secure because they are sealed

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rior to being shipped and are only opened once they have arrived at their destination.

These cont

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

iners are being used to ship a variety of different goods across the globe. From food products to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

personal care items and machinery, the freight shipping industry is increasingly using steel conta

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ners to transport freight.

The ability to move large volumes of freight easily and cheaply is vit

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

lly important for countries like South Africa that are experiencing huge growth in freight traffic

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

. Indeed, in the case of South Africa, traffic has exceeded the 20 year growth forecasts 14 years

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

arly!

The use of steel containers by freight shippers grew by a staggering 54% in South Africa be

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ween 1998 and 2005. It is estimated that the use of steel containers for freight shipping will con

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

tinue to increase by around 15% each year between 2010 and 2015 in South Africa.

The reliance on

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

teel containers by other freight shipping nations is also set to increase. Analysts predict that t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e global use of steel containers will increase by 6% year on year between 2015 and 2015.

The reas

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

on for the heavy reliance on steel containers for freight transport seems to be attributable to a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

umber of factors. For instance the use of steel containers makes the shipment of products cheaper

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

nd easier. Whilst the emergence of the European Union as an important trading block has accelerate

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d international trade.

The use of containers has been critical to the growth of global trade and

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

he freight shipping industry. It is likely to continue to be important for many more years to come

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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