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One of the most common ways that carwash owners like to advertise their busin

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ess in their local communities is to use direct mail marketing advertising in

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

those little coupon booklets that are sent out. These work very good howeve

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

r, there are few things that you should consider.

First, you do not want to

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

give away too much of a discount and then have all those people show up on a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

busy Saturday when you are already slammed with customers. Instead you want

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

to make an offer where they have to come on a Monday to stare Wednesday to re

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ceive a discount. If the booklet of coupons comes to the home on a Thursday t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

his is not so great for your business. But if it is delivered on a Monday wit

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

h a big coupon discount, only to be used on Mon-Wed then this could be quite

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

good.

Additionally, if the forecast is for heavy rains and you give away too

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

much of a discount then the rain will stop and all of a sudden everyone will

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

show up and want a carwash and the people who received a direct-mail marketi

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ng coupons will also show up at the same time and that is exactly what you do

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

not want; more business.

I have talked to some carwash owners who at the la

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

st minute will pull their coupons in the coupon book because there is a huge

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

forecast for rain the day they will be delivered and that means as soon as th

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

e weather clears everyone will be at their carwash anyway and therefore the c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

oupon will not help their business only make matters worse because there will

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

be too much business all at the same time. Please consider all this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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