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Many times small-business people complain that their direct-mail marketing a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

dvertising is working too good and that everyone who comes in seems to have

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

a coupon and no one seems to be coming in who doesn't have a coupon. There

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

could be a couple different reasons for this.

One reason could be that your

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

customer service is very lousy and even though you bring in new customers n

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

o one ever comes back. But the second reason is probably the most likely and

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

that is that you use direct-mail marketing so often and so much that people

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

only come in when they get the coupon in the mail, which they expect every w

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

eek or two times per month, so they wait for it.

If this is happening to yo

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

u perhaps you need to limit how much you give away on your coupons and slowl

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

y break your customer's coupon addictions. You want the customer to be addic

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ted to your great service and or your products and services, not the coupons

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

that you send out in the mail.

The objective of direct-mail marketing is t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

o get the customer in to buy from you and introduce them to your business.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hen get them to come back and shop with you more often. But if you consiste

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ntly send out coupons, they will simply wait until the coupon comes in the m

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ail to come and shop with you.

This does not help your business very much,

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

as it costs you money to give away discounts, send out the direct-mail adver

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tising and you're not getting a long-term benefit that you need for the ongo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ing vitality and success of your business. Please consider all this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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