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For a small-business owner they know that a big banner in front o

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

f their store with advertising will help them sell more products

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

or sign up more people for service. Some cities and towns have o

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

rdinances that do not allow small-business owners to put up the b

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

anner ads all year round. Instead they are only allowed to do it

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

so many times per month.

This is why sometimes it pays to look

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

at multiple ways to advertise to promote one's small-business. Wh

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ch works better; Direct-mail marketing in those little coupon adv

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ertising books or a gigantic big banner in front of the store?

T

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hey both work very well is specially if the store is on a Main St

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

reet and well known in the community. If the direct-mail marketin

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

g piece is sent out to all the customers within a 10 mile radius

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of the store then those customers are more apt to come in shop if

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

there is a discount worthy of mention.

Okay then, how often sho

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ld direct-mail marketing pieces be sent out in the coupon booklet

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

s? Well, perhaps once per month if each month the small-business

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

owner picks a different type of discount.

This will generate ne

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

w traffic and new customers and perhaps those customers will beco

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

me regular customers. That should be the goal of direct-mail mar

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

keting advertising. I hope you will please consider this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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