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As consumer-buying power widens, so are shopping options. Included in those ioptions a

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

re mail order catalogs. Started by Aaron Montgomery Ward in 1872, this line of shoppin

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

has brought millions of products to many consumers who prefer to shop at home. As a t

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

avelling sales man, Aaron Ward realized that his rural customers, the fishermen and fa

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rmers could be better served by mail order. This innovation proved to be a revolutiona

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

y idea as the single paged catalog expanded to 540 paged illustrated publications sell

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ng over 20,000 products. The publication of this catalog bears similar resemblance to

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the publication of magazines and is also distributed usually via postal service or via

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the Internet.

As mentioned earlier, the first mail order catalog created by Aaron Mon

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

gomery Ward. It was a single sheet of paper containing certain products and their corr

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

sponding prices. Ordering instructions were also written on this sheet of paper. This

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

catalog eventually expanded with more merchandises to choose from. Soon the Eaton’s D

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

partment store in Toronto, Canada followed this booming business in 1884. A decade lat

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

r, the Sears Catalog was published.

One advantage of shopping from mail order catalog

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s is that consumers are guaranteed that the products are much cheaper compared to thos

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

sold in a regular department store. It is probably because merchants are not typicall

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

required by law to add taxes on their products. This eliminates miscellaneous expense

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

s charged by the merchant, the government and the supplier.

With the discovery of the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Internet, several companies have created their own website and list a vast number of c

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

talogs for each product line. This is now referred to as E-Commerce or online shopping

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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