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If you run a non-profit business then perhaps you should try direc

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

t marketing and direct-mail to get volunteers and increase donatio

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s to your non-profit. Direct-mail and direct marketing does not j

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ust work for businesses, as it is a way to catch people in their h

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

mes who read direct-mail and direct marketing packages.

Some peop

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

e think that direct mail and direct marketing are mostly for local

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

small businesses in the area to send out to high net worth indivi

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

uals in specific demographics within target areas of zipcodes. It

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

is true that direct-mail and direct marketing packages do work wel

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

l for many types of small businesses in both the service sector an

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

the retail sector. But direct marketing and direct-mail is not j

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

st for businesses, as it works very well for public announcements

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

of water conservation or other important issues and it has been us

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

d by politicians and government agencies for years.

I recommend t

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

at if you run a non-profit group that you consider direct-mail or

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

direct marketing mail outs to promote to your endeavors. It is not

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

easy staying up on the needed funds that nonprofits must have to s

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

rvive. It is not easy recruiting volunteers, which will work very

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

hard in your organization. Direct-mail and direct marketing can

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

elp you achieve your goals. I hope you will consider this in 2006

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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