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What is Thai silk really?

The Chinese kept the secret of silk for thousands of years! Truly it is an exclusive fabric and back to the past it was only for the high society and kings. The secret was protected by enfo

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

rcing dire penalties. Anyone found guilty of smuggling silkworm eggs, cocoons or even seeds of the mulberry tree was put to death.

A secret doesn't remain secret forever. The production of Thai silk begins with a sm

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ll worm know as Bombyx mori: the silk worms coming from the eggs from the silk moth. The worms are eating the leaves of mulberry trees until they become 1 year old, after they will build a cocoon from their spittle.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

To extract the silk thread, we have to put the cocoon in hot boiled water. The length of silk thread in a cocoon varies considerably, from 500 to 1,500 yards. The length much depending on the species of worm that pr

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

duced it. ?Until today in Thailand, most silk thread is hand-reeled by women, the filaments form several cocoons being reeled together on a wooden spindle into a uniform strand of raw silk.

It is truly a time-cons

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

uming process.?It may take up to 40 hours to reel one and a half kilograms of silk. Several sericulture families have simplified the job by using a reeling machine. Most traditional manufacturers, however, still use

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

he old or “original” method, which produces three grades of silk: two fine ones suitable for lightweight fabric and a thicker one used for heavier material.

The skeins of silk thread are then soaked in hot water to

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

emove the remainder of the seracin. Since Thai silk yarn is yellow, it must be bleached before dyeing; this is done by immersing the skeins in large tubs containing hydrogen peroxide, after which they are washed and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ried in the sun.

Thai Silk is then woven on a handloom, the threads (warps and wefts) that pass across and are inserted during the weaving process. Thai Silk is hand-woven fabric, which means that although if confor

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ms to set standards of width, color, and quality it still retains a degree of individuality impossible to achieve by more advanced technology.

Cleaning & take care of Thai silk

Thai Silk has an excellent durable an

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

resilient quality. It is a delicate fabric that cannot be treated like linen or cotton. To keep the fabric in its original look and feel it is recommended to do dry-cleaning. Wash Thai silk best by hand by using a v

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ry mild soap. Rinse the silk fabric in tepid water (not over 48.6 degrees Celsius) until it is cleaned. Then carefully press the water from the fabric by hand.?Do not wring. In the last rinse, add a spoonful of clear

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

white vinegar to retain its original luster and allow it to drip dry in the shade.

Important:
Please do not use any drying or washing machine to clean your Thai silk item. We advise to iron the fabric on the re

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

verse side just before it is dry; or you could also put a fabric over the silk during the iron process to make sure the iron does not have direct contact to the silk fabric.

Indetification of real Thai silk

Simply

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ollow the four main methods for determining true silk:?

-A) The Price
-B) Look & Feel
-C) Luster Check
-D) The Burning Test

A) Real Thai silk cost up to 10 times more than artificial silk.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

) One fact is that traditional Thai silk is hand-woven which means that no fabric is the same, and each one is unique. Artificial silk is machine woven, so it has always the same color and every part of the fabric lo

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ks exactly the same.
C) Luster also shows whether a fabric is real or imitation. Pure Thai silk is made with one color for the warp and the other for the weft. This produces the sheen and luster and additionally

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

creates the unique two tones and blends. The change of the color is then depending on the angle you hold it against the light.
D) If you burn silk with a flame, it leaves fine ash and smells like burning hair.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e remember silk is made of natural fiber coming from the silk worm and similar to the fiber of hair or fingernails. Once taking the flame away it stops burning. Burning artificial silk is similar to burning plastic,

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

he smell, reaction to fire and look.

Read also our information about Thai Silk Shawls at http://www.designerbags.de/thai_silk_shawls.html

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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In the previous article we discussed the over rules of an institution in comparison with the covert rules. Now that you have had time to explore the overt rules thoroughly, it is time for you to explore the covert rules. One must know the overt rules very well, before one can see the covert rules, because they are just about invisible and they are usually in opposition to the overt rules.

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