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Digg It - Greatness and the Silicon Valley Gold Rush
Imagine you are rich. Very rich. Obscenely rich.
Normal people in normal parts of the world only imagine being that rich at an abstract level. They don’t really believe it is possible. Or at least, they don’t structure their lives around the expectation of being obscenely rich.
In the mid-nineties, a phenomenon happened here in
Normal people in normal parts of the world only imagine being that rich at an abstract level. They don’t really believe it is possible. Or at least, they don’t structure their lives around the expectation of being obscenely rich.
In the mid-nineties, a phenomenon happened here in
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
Silicon Valley, which defied all laws of market economics. Companies could be successful without having to make money or be profitable. Success meant Billions of Dollars in market capitalization, and consequently, very rich Venture Capitalists, founders, executives and employees.
Even receptionists, during this time, could conc
Even receptionists, during this time, could conc
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
eive of making Millions. (Just to put it in perspective, a receptionist in India makes about $2000/year.)
People started believing that being rich was their birthright. It was no longer thought to be an exception, or a mark of extraordinary brilliance, vision, effort or leadership. It was more, being in the right place at the ri
People started believing that being rich was their birthright. It was no longer thought to be an exception, or a mark of extraordinary brilliance, vision, effort or leadership. It was more, being in the right place at the ri
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ght time.
This was the California Gold Rush, replayed in Internet time.
Then, the nineties rolled into the Millennium. Rational thought prevailed. Wall Street crashed, taking with it over 3 Trillion Dollars of investor wealth. All those who grew up in the (brief) age of eternal optimism, mad euphoria, and unrealistic expectatio
This was the California Gold Rush, replayed in Internet time.
Then, the nineties rolled into the Millennium. Rational thought prevailed. Wall Street crashed, taking with it over 3 Trillion Dollars of investor wealth. All those who grew up in the (brief) age of eternal optimism, mad euphoria, and unrealistic expectatio
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
ns, were suddenly halted in their Porches. They had to stop and rethink. Adjust their expectations, plans, career-tracks, and suddenly, $600 bottles of wines started disappearing from cocktail party conversations.
For people who live outside Silicon Valley in particular, and the technology world in general (there have been some
For people who live outside Silicon Valley in particular, and the technology world in general (there have been some
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
demonstration of similar phenomena in Boston, Seattle, New York and other places to a lesser degree), this period held enormous intrigue. The before, the during, and the after of the gold rush, together represent a period that will go down in history as one that bred and nurtured greatness and wealth creation.
Greatness is impor
Greatness is impor
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
tant. An entrepreneur in Silicon Valley once said to me, It is better to be lucky, than to be good. I couldn’t disagree more. Luck is not and never was a repeatable event. Luck is not what builds greatness. Greatness is more fundamental, more intrinsic, and more rare. Hence, to me, greatness was the significance of this period. W
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
alth was a by-product.
I was asked to write this article for a Spanish Journal to discuss the differences between Eastern philosophy and American philosophy. So, at this point, it would be a good idea to give the reader some background on who I am, and what experiences have shaped my perspective. I do not wish to comment on Ame
I was asked to write this article for a Spanish Journal to discuss the differences between Eastern philosophy and American philosophy. So, at this point, it would be a good idea to give the reader some background on who I am, and what experiences have shaped my perspective. I do not wish to comment on Ame
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
rican philosophy and Eastern Philosophy in general. America, especially California, is a huge mish-mash of so many different contexts and personal histories, that it makes no sense to call any philosophy American. Rather, I shall share with you my personal philosophy, which I believe is a mixture of the East and the West.
I grew
I grew
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
up in Calcutta, India, immersed in the philosophy of my favorite poet and thinker, Nobel Laureate, Rabindranath Tagore. At 18, I left India, and started college in Massachusetts. Subsequently, I went to University at MIT, and then became an entrepreneur. My father was an entrepreneur, so this path was a natural choice for me. Ch
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
ronologically, my entrepreneurial career synchronizes with the Internet revolution. I started, built and sold several companies over a span of 6 years, and lived in the heart of this Silicon Valley phenomenon.
In my upbringing as the daughter of an entrepreneur, the psychology of pursuing dreams at all costs and dealing with all
In my upbringing as the daughter of an entrepreneur, the psychology of pursuing dreams at all costs and dealing with all
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
the consequences - failure, defeat, disaster, pain, suffering, glory, celebration, faith -- was life. I neither looked for luck as the primary driving force in my life, nor accepted it as a lasting factor when I was, indeed, very lucky. My approach was always to push myself to learn, and to become better, so that I could accept,
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
within myself, that success is earned, not inherited, and not a chance factor. And then, I had faith. In myself. In my dreams. In my destiny.
I have often looked at Tagore’s life and work, for guidance, for philosophy. Tagore was a sensitive person who possessed enormous capacity to feel at great depth. His music, his poetry, h
I have often looked at Tagore’s life and work, for guidance, for philosophy. Tagore was a sensitive person who possessed enormous capacity to feel at great depth. His music, his poetry, h
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
is novels, essays, short stories [some 25 Volumes of prolific, profound literature] demonstrate how he derived music from every blow - every death, to be more precise. His first love, his wife, several of his children - all died in course of his lifetime. And those moments of his greatest suffering, most cutting pain, produced hi
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
works of maximum intensity.
Tagore lived during the period of India’s freedom movement. The poem below is his vision for a free country.
Where the mind is without fear and the head is held high
Where knowledge is free
Where the world has not been broken up into fragments
By narrow domestic walls
Where words
Tagore lived during the period of India’s freedom movement. The poem below is his vision for a free country.
Where the mind is without fear and the head is held high
Where knowledge is free
Where the world has not been broken up into fragments
By narrow domestic walls
Where words
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
come out from the depth of truth
Where tireless striving stretches its arms towards perfection
Where the clear stream of reason has not lost its way
Into the dreary desert sand of dead habit
Where the mind is led forward by thee
Into ever-widening thought and action
Into that heaven of freedom, my F
Where tireless striving stretches its arms towards perfection
Where the clear stream of reason has not lost its way
Into the dreary desert sand of dead habit
Where the mind is led forward by thee
Into ever-widening thought and action
Into that heaven of freedom, my F
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
ather, let my country awake.
This to me, is a vision for life in general. A search for greatness.
In my Silicon Valley years, I have encountered greatness in many people. I have, also, encountered mediocrity in many forms. Mediocrity searches for luck before excellence. Greatness searches for excellence, always. Wealth is incid
This to me, is a vision for life in general. A search for greatness.
In my Silicon Valley years, I have encountered greatness in many people. I have, also, encountered mediocrity in many forms. Mediocrity searches for luck before excellence. Greatness searches for excellence, always. Wealth is incid
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
ental, not the end game. Luck facilitates the process of creation that is the destiny of greatness.
Faith in personal capacity for greatness is part of both the East and the West. Eastern philosophers say that God is inside man. The infinite potential for divinity is in the soul, which dwells within. Western Capitalists believe
Faith in personal capacity for greatness is part of both the East and the West. Eastern philosophers say that God is inside man. The infinite potential for divinity is in the soul, which dwells within. Western Capitalists believe
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
in the infinite ability of the individual, driven by ego or the desire to build, to innovate, and to leave a mark.
So, as Silicon Valley struggles with its current reality, perhaps, it would be appropriate to step back and celebrate the instances of greatness that have happened, and help young professionals refocus their philoso
So, as Silicon Valley struggles with its current reality, perhaps, it would be appropriate to step back and celebrate the instances of greatness that have happened, and help young professionals refocus their philoso
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
phies and quests to emulate those who have sought greatness, rather than those who have sought instant riches.
And for the outside world that looks, still, at Silicon Valley, with wide-eyed wonder and awe, it would be appropriate to understand what makes Silicon Valley’s DNA sustainable.
It is the search for greatness, not gold
And for the outside world that looks, still, at Silicon Valley, with wide-eyed wonder and awe, it would be appropriate to understand what makes Silicon Valley’s DNA sustainable.
It is the search for greatness, not gold
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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