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When your business is offering a service, you have to determine how many clients you'll need in order to reach your goals. In the beginning, you needn

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

’t have a group of ready-made clients, but it helps if you have a good network of people whom you can approach, asking them to become clients.

Start

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

by making a list of your current clients, including clients to whom you give free services. From this list, estimate how many would be willing to pay

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

or your product or service (versus getting it for free). Consider how many of these people can afford to pay, if that is an issue among your client ba

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

se. Also, ask yourself if any of your current clients are "repeat" clients, meaning they have hired you more than once in the past year or two.

Next,

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

think "networking." How many people do you know who you can call, to tell them about your business, even if they have never bought your services or pr

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

oducts before? Include in this list the following people: family, friends, business colleagues, members of your neighborhood or community, and people

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

you purchase products and services from. Let's say this list totals 40 people. Imagine if you tell 40 people about your services and products, and ask

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

them to tell five others, you will have reached 200 people.

The next step is to determine how much money you need to make. Take a look at all your li

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ving expenses and decide if your business is intended to support your financial needs completely, or if you will get another job to support you while

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

our business is growing. Determine your fees and do the math to figure out how many clients/sessions you have to do per year (or how many products you

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

have to sell) to make your living expenses.

For example, say that you are a Piano Teacher, and need a total income of $50,000 per year ($35,000 prof

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

it per year after taxes and expenses). If you are going to charge $60 per hour, you'll need to do about 833 hours per year. This is equivalent to 69 h

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

urs per month, or 17 hours per week, or 3-4 hours per day (using a 5-day work week). If that's too many hours per day, you will either need to increas

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e your prices, or lower your expectations of total revenue. If that hourly fee is higher than your competitors', you'll have to re-think your hourly f

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

e AND the number of billable hours you have. (You can do this same math if you sell products instead of services.)

So let's say you need 833 hours pe

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

r year to live comfortably. Does that mean you have to find 833 individual clients? No, not really. Depending on your profession, you will have a cert

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ain number of repeat clients who may come to you once a week, once a month, or once every six months. If you have really good marketing, you can incre

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

se this number of repeat clients because you will remind them that you exist with mailings and phone calls. Remember, it's cheaper to market to existi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ng clients than to new, prospective clients.

Take the time to do the math. Figure out how much work you have to do in order to live the life you want

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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