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1. Understand what you mean by intrapreneurialism in your corporation.

Before setting out to create this environment you had better know exactly what is sought. What are you looking for from your staff and what are the desired results?

2. R

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

evisit your corporate vision, mission and values (or develop them!).

Appropriately chosen and fully understood, these help staff understand where your company is going and which opportunities might represent the stepping-stones. Your values

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

efine the behaviours and standards expected to be demonstrated in everything done in the corporation's name. Are your corporate vision, mission and values appropriate for developing an intrapreneurial environment or do they need amending?

3.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Is your workplace free of interdepartmental and interdisciplinary turf-protection?

If your people are to be continually alert to opportunities for all departments of your corporation, opportunities which they ensure are followed up, there i

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

no room for action to be compromised by petty jealousies. Think of the way in which teamwork too will benefit following elimination of these toxic emotions.

4. Review your staff retention figures and do what is necessary.

Why would you dev

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

lop the nation's most intrapreneurial staff only to have them hired away by the competition as soon as they become effective? Compare your staff turnover with similar corporations, practices, businesses and strive to be the continental leader

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

in staff retention. Look at the quantity of work and number of staff. Are the figures compatible? Consider wages, salaries, working conditions, staff training and development, the degree to which your people are acknowledged and encouraged to

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

stretch in terms of personal and professional development. Do what is necessary to make your corporation a Sustainable Workplace(tm).

5. Develop descriptions of your target markets, target clients for today, tomorrow and the era beyond.

Con

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

inually collect information about your target markets. Not only who, what, where and expected developments but what do its representatives read, where do they go and what can you contribute to help them reach their goals? Who are your most pr

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

fitable clients or accounts today? How do you see this changing in future? Who do you enjoy working with? What new markets are you anticipating? Is there a client sector which creates so much friction you will not serve it? Who do you want to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

add to your client list? Who do you want to delete?

6. Do all staff understand the range of services and products offered by your corporation?

How can opportunities be maximised unless everyone understands what the corporation produces and

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ants to produce? What sort of problems does your business solve? Ensure that all staff, regardless of their positions, can describe these characteristics of the corporation and more importantly, their benefits for customers. Give everyone in

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

he company the language of your industry regardless of their primary responsibility and why not include some of your suppliers and customers/clients to enable them to make referrals with more confidence?

7. What guidelines will you give staf

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on the time to be spent on intrapreneurial activities?

Your staff are already fully committed during the working day applying the primary skills for which you employed them. How much time may they devote to intrapreneurialism and when? Will

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

each person follow up the opportunities they recognise or alternatively refer them to a designated person or department?

8. Collect stories supporting your corporation's expertise.

Ensure that extraordinary achievements during each campaign

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

project, contract, start-up are recorded: the 'firsts,' unique approaches, innovations, incredibly fast deliveries, techniques which significantly reduced costs or increased quality. This information adds zest to promotional and networking c

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nversations and is also great ammunition for brochures and responses to Requests For Proposals.

9. Install systems to support the intrapreneurial effort and avoid duplication.

Ensure there is a model for ensuring that each lead is followed

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y one person only. Arrange a referral model for people able to recognise opportunities but less comfortable in pursuing them. What else do you need to have in place? Do it!

10. Reward intrapreneurialism.

How can you encourage an intrapreneu

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ial attitude among your staff without the rewards of successful entrepreneurialism? Alternatives are not limited to financial incentives. Options might include involvement with the project, recognition before peers, a celebratory dinner for s

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

affer and partner complete with limo service, donations to staffer's favourite charity, a leader's jersey/T-shirt/jacket based on the idea of the Tour de France's 'maillot jeune.' Are there reward alternatives uniquely right for your business

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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