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There’s nothing that matches the power of teamwork to accomplish amazing results beyond your wildest goals and aspirations. Teamwork evokes unflagging spirit, selflessness and dedication. If any one watched one of the CBC reality shows serie

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

s of “Survivor” you could viscerally feel the power of teamwork in action. This particular show was set with all the “superstar” survivors. They were single, powerful players with well honed survivor skills. The game changed when two player

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s formed a much deeper alliance becoming a couple. As their bond grew the caring, support, and selflessness heightened their senses as they strategized to win. The other ‘trojans” became almost laughable, as mere pawns of the couples’ strate

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ies. The couples results were stunning. They won almost every “challenge” they faced.

In the end they were the last two remaining survivors. At which time he proposed to her so they both won the million dollar prize and all the other prize

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

s along the way. Not to mention the commercial endorsements they probably won becoming “suriviors” first couple. The show actually became laughably predictable as you watched their power play out.

The take home: create a deeper bond by set

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ing goals together and get strategy. Set New Years Resolutions together!!! Set goals and discuss them together. Give yourself mutual goals and work on them as an ongoing project. Don’t keep it to yourself, share, share, share.

Both partn

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ers find pictures of how you want to look. Put them up on your fridge or where you dress and internalize that vision. Set a date to accomplish this goal and discuss what it will take to get there. You’re a team with a project and a real go

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

l. Now plan your strategy. Map your meal times, foods, workout regimes, how you’ll handle certain situations. Share your weaknesses so you have a partner who’ll help you overcome them. Monitor your progress. Compare and support each oth

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

er's results, setbacks and improvements.

Make it fun! Make a bet “if I reach 24% body fat by this date you will come with me to the opera 4 times this year and I’ll go to 4 jets games with you if your bodyfat reaches 12% ” Talk about why

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

you need to accomplish this goal, let your partner feel your pain, then he or she will be on your side feeling for you, supporting you. Get you partner to share their weaknesses for you to support. No one wants to be nagged and no one wa

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

nts to nag, so it’s just a matter of getting into "this is for us", make an alliance and get strategy. Your partner is your live in coach and therapist. Work together, strengthen your bond, deepen your relationship, and set your strategi

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

es. Not only will you reach your goals but with the power of team work, only your imagination limits what you can accomplish.

Never Think Like a Victim, You're Always in Control. I often hear “Oh my husband always has a drink and I feel I

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

have to have one with him.” If you blame your husband you are making yourself into a victim! You always have a choice.

If my husband drinks and wants me to join him, I just say “no thanks, I’m having a Pellegrino with lime, Cheers” I get

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

my buzz caring for my needs, he gets his and we’re both happy. I don’t have to change him nor him me. No blame. No resentment. We respect and admire our differences. I also hear “My husband comes home late to eat dinner and though I’m not

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hungry I sit down and eat with him again. “ My strategy is I know he’ll be late so I save something to eat with him and chew slowly (it comes with listening). If I’m doing all the talking I hardly eat.

“When I go out to a restaurant they al

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ways serve these awesome fries with the food.” You know it’s coming and you’ll be too tempted to resist so tell them to substitute the fries with a grilled veggie. The same thing goes with bread! Order a veggie or protein appetizer instea

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

.

“When the kids come home from school I have to feed them and I end up eating their left overs.” If your concerned about waste think of the expense of burning these extra calories and how you’ll ruin the really good stuff at your dinner.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Not to mention the extra cardio time tomorrow or the cost of an extra training session. You might be better off planning your snack time with the kids time and prepare a small protein snack for yourself instead of eating those fat making c

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

rbs. That way your sated while you feed the kids stopping temptation. Plus you'll have room for the good stuff later on.

If you absolutely have to have a drink avoid the sugary ones, drink slowly, drink wine and enjoy it, cut the carbs in

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

you entre and know you have to pay in cardio time tomorrow.

My husband has forbidden foods everywhere in my kitchen, and in my mind I just label them ‘Johns’ or ‘inedible’ with a big X over them…this works for me, they’re just not my choice

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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