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    In today’s world when Corporate are struggling for profits and with fierce competition in the market, co
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    st reductions, productivity enhancement and lean organizations have become today’s mantra s for survival
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    Folllowing are the key area where you can implement cost reduction methods with significant results.

    1.
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    Raw material procurement:

    2. Logistics- Inbound and Outbound:

    3. Warehouse and Stores:

    4. Manufacturi
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    g Process (Production) :

    5.Energy, fuel & Water

    6.Information Management

    7. Finance

    8. Human Resourc
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    s

    8. Sales & marketing

    FEW BASIC IDEAS PROCUREMENT

    IT CAN BE DIVIDED INTO TWO MAJOR GROUP

    A. PRODUCT
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc


    B. SERVICES

    Raw material purchases constitute around 60-65% of the cost of product; hence any savings
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    on this front would be significant for profit of the organization.

    1.BULK BUYING:

    A. The company which
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    has units spread across the geography can negotiate better price when the volumes are high, instead of b
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ying for individual units its recommended to have central buying policy.

    B. You can negotiate better pr
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ce if you can put your entire annual consumptions to a vendor and ask him for annual rate contracts. You
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    can then ask vendors for staggered deliveries at one or various ocation . Companies with larger geograp
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ical presence are best suited for such plan . You might have seen that they all have central purchase te
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    m . Bulk buying should be supported by bulk handling and storage system.

    2. OPPORTUNITY BUYING : All ra
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    material have a cyclical nature of price .for span of twelve months prices would be high for some month
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    and would be low for the balance month the plan is to buy maximum when the prices are low . by doing th
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    is you can save a lot .

    3.E-PROCUREMENT : With advent of internet and websites it is now possible to pl
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ce tenders ,requirement on website online and get bidding , quotation online which enables buyer to reac
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    to wider base of vendors or suppliers .Which also enhances buyer negotiating space for price.This devel
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    pment has helped buyers to cut cost which otherwise would have been spent on conventional way of tenders


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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