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The gains we get from increased productivity come to us in two main ways: higher wages

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

, or less expensive products. Let's take a look at one product that costs less and del

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

vers more value because of higher productivity:

When I grew up in the 1950s, everyone

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

in the neighborhood took notice when a new television set arrived. The cost of a set

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

epresented a big portion of a family's income.

And then there was upkeep. In those da

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

s, we could count on our TV sets to make a funny noise and go black just before the ca

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

r chase came to a climax, just before the big wedding on a soap opera, or just before

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

he championship game. So we called a TV repairman, who came to the house, replaced a t

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ube or two, and gave us a bill for which we hadn't budgeted.

On the other hand, when

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ou go to a discount store and buy a new TV set, the cost likely represents less than a

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

day's pay, and you'll probably never call a repairman (assuming you could even find on

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

e). Your set will last for many years, and when it shows its last commercial, you will

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

simply throw it out and buy a new one. In effect, TV sets have become so inexpensive t

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

hey're a disposable product.

Our television sets are just one of the many products th

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

t cost less, at least in real dollars, because of productivity improvements. If we loo

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

through our houses we will see many products that effectively cost less and do more t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

han they did a generation ago.

We might even say that the greatest television story e

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

er told is one you won't see on the screen; it's the story of a half century of improv

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ements that pulled the real prices of television sets way down, and pushed product qua

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ity way up. And that's true of many household products, especially electronic products

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Digg It - Productivity: The Greatest TV Story Ever Told

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