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How many times have you subscribed to a new ezine, and then when the first issue of the ezine arrived, you were scratching your head as to how your emai

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

l address ended up on the list? Our lives are often so tedious that little details often slip right from our memory.

The point is this. If it happens t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

you, you can rest assured that others have the same experience as well.

Sometimes when this happens to us, we just unsubscribe from the list after tha

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

t first issue. We cannot remember what compelled us to subscribe in the first place, and the first issue of the ezine does little to rekindle our initia

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

enthusiasm for the ezine.

As publishers, autoresponders can serve us well. When used correctly, autoresponders can strike while the iron is hot, cem

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

nting the subscription for the new subscriber.

If your ezine has been around for a while, or only for a few issues, seriously consider taking the time to

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

compile a *Best Of* issue.

Be certain to list subscription instructions near the top of your *Best Of* issue, and also ask people to forward it to t

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

eir friends.

Your *Best Of* issue should be placed into an autoresponder email address, and then given away at every opportunity. The moment the issue

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

is ready, you can notify your subscribers of the existence of the issue. In the ezine information area of each issue, you can also remind subscribers th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

t the *Best Of* is available at such-and-such email address. Ironically, some of your subscribers will download your *Best Of* several times.

The most

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

mportant reason for building the *Best Of* issue is not for the benefit of your current subscribers, though most of them will appreciate your making it

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

available to them. The best reason to implement the *Best Of* autoresponder is for your new subscribers!

When someone subscribes to your ezine, they wi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

l receive their *Welcome to My Ezine* notice. As they are reading the *Welcome* message, their enthusiasm is bubbling over. Waiting for that first iss

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ue will be tough unless there is an invitation to receive their first issue NOW.

In your *Welcome* message, you should let them know that if they would

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

like to get started right away reading your ezine, then they should send a blank email to your autoresponder address for the *Best Of* issue.

New subsc

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ibers will gorge themselves on your *Best Of* issue, and they will remember your ezine when the first new issue arrives in their mailbox. If the *Best O

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

f* issue was precisely what they were looking for, you can rest assured that they will eagerly open each subsequent issue of your ezine, with delight

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

n their hearts.

If you do not have the ability to set up autoresponders on your own domain, one company that offers a free autoresponder service is: ht

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

tp://sendfree.com/

If you take the time now to implement the *Best Of* autoresponder, the rewards will most certainly be long-lasting. Remember, the be

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t time to get a new subscriber to fall in love with your ezine is when their interest is the highest --- at the very moment they subscribe to your ezine

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Listening is the least used skill by most sales people. Everyone wants to talk about products and services, features and benfits. It's the sales person who listens that gets the best customers.

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