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    The 1st line of your email is, often, not the first line at all. The email b
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    egins with the Subject Line, which must be considered as your most potent ma
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    keting weapon. A single line – often less than 10 words – will determine if
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    your email is going to be opened and read, trashed and discarded. The Subjec
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    Line must inform the reader about the email and your reason for sending it.
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    Avoid Subject Lines like –

    - Hi
    - Empty fields
    - Or abrupt ones
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    ike ‘Inform’ or ‘ Reply’
    - ‘Fwd:’ which looks like a joke or a forwarde
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    d email

    Everyone is submerged under dozens of emails, and people are strugg
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ing to deal with spam as well. So if you want your email to be opened and re
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    ad, use the following strategies in your Subject Line -
    - Ask question
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    like ‘Is your PC Secure’
    - Answer queries like ‘Yes, I Did Lose 10 Kgs
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a

    - Summarize your email with ‘Minutes of the Meeting on 10/09’

    The bod
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    y of your email should avoid long winded sentences and endless paras. Use bu
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    leted points, bold important points, use headers like ‘Things to Do’, etc. M
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ake your email easy to skim through by avoiding flowery language and too muc
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    information. Be concise clear, to the point, and brief.

    End your email wit
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    h a call to action. Do you want a reply, a phone call, an action to be taken
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    a meeting to be called? Or is no action required? Well, say so. And then en
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    d with your contact numbers, email IDs, URL, cell phone number, and the name
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    of your company. It’s a good idea to attach a v-card or a standard signature


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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