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Do you wonder what is the most appropriate way to sign-off your e-mails?

The topic of how to sign-off an e-mail is one that has perplexed and concerned many a Netizen. Those who are concerned ab

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

out being perceived favorably wonder about how to leave the appropriate tone, close with the intended meaning getting across as well as how not to look redundant by always including the same closi

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ng.

First things first. All sign-offs need to include your name. Whether you include your first name alone or first and last name is dependent on the level of formality in your e-mail. For fir

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

st time contacts you can include your last name, but in subsequent communications that isn't necessary. If you have your e-mail program setup properly, your last name is in the From: field.

Not

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

nly does how you sign your name set the tone of an e-mail, so does how you choose to sign-off. Some have their own way of signing off that reflects individuality or their personality. For example

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

I am known for signing off my e-mails with "At your service," or "Virtually,". If you see anyone else using these closings, you now know where they got it from!

Then there are the most popular:

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

Best, Yours, Cordially, Regards, Best regards, Best wishes, Sincerely, Kindest regards, Warmest regards, I remain yours truly, Warmly, Thanks again, My sincere thanks for your time a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d consideration, Take care, Continued success,

You wouldn't use "I remain yours truly" in business communications, but you would use that closing with someone you admire, like or would like to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

have a friendly e-mail relationship with. Whereas "Regards," is the other end of the scale. Very professional, unemotional and depending on the content of the e-mail could be perceived as a ters

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e closing.

One must take the time to choose a sign-off that is indicative of the overall tone of your e-mail. A sign-off that does not match the essence of the e-mail's text can be perceived as

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eing sarcastic or down right rude. For example, I doubt if you were sending a professionally stern e-mail that you would sign off with "Warmly!"

And that is the dilemma we all face when writing

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

and closing our e-mails. Using our discretion to determine the best words to use to relay the exact tone and intent with clarity to avoid misunderstandings. From how you open your e-mail with a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

salutation to the content and then the sign-off, all parts of your e-mail are a component that contributes to the overall interpretation of your message.

Most onliners are not clear communicators

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

. If you think about it we haven't had to rely on communicating with the written word in decades. Just a mere century ago people wrote letters daily. This meant choosing their words carefully a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

d thoughtfully to communication the emotion and intent of their writings. Now, fast forward this century and many e-mails appear to be written by someone who didn't make it out of grade school!

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

The above 7 examples are not the end-all-be-all either. Your sign-off isn't exclusively the words above your name separated by a comma. You can also use phrases that reflect the purpose of your

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

e-mail as well. Some examples could be:

Good Job!
All the best of success!
Have a great day!
Happy Holidays!
Keep up the good work!
Thank you!
Thank you for you

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

quick response.
Thank you for taking your time.
Looking forward to your reply.
Enjoy your weekend!
HTH! (Hope This Helps!)
Have a good one!

Your closing, while very

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

important, is only the icing on the cake. It needs to be inline with the overall tone and demeanor of your e-mail to ensure that your message is delivered with clarity and leaves no room for mis

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

understandings or incorrect perceptions.

By taking your time and choosing your words carefully your sign-offs will just be one more indicator of what a pleasure it will be to communicate with you

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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