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Ever wonder how flowers get fertilized without being able to move around? S

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ome flowers can only be fertilized by pollen from another flower. This proc

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ss is called cross-pollination. Amazingly, these flowers get the pollen the

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

need from other flowers without having to move an inch. How? Bees bring th

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

pollen.

The bees crawl around in one flower and get covered with that flo

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

er’s pollen. Then the bees fly to other flowers and crawl around in them, l

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

eaving behind the pollen, fertilizing the other flowers in the process.

Th

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

one flower “sends” the pollen. The other receives the pollen. Neither move

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

anywhere.

That’s what email is like.

One person sends something (a messa

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e) and the other person receives it, while neither person had to move at al

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

. In the case of email, the thing that’s sent is carried by a specific part

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

of the Internet that delivers email messages.

But email is slightly diffe

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ent than the bee example in that the message doesn’t go directly from one p

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rson to the other. Instead, it stops in the middle at a server, which is ju

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

t a computer hooked up to the Internet. The message waits there until the o

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

her person is ready to receive it. So it’s as if the bee gets the pollen, t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

hen waits by the lily pond until the second flower says it’s ready for the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ollen.

Another difference is that unlike with the bees, using email doesn’

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

lead to getting fertilized – but of course that depends on what type of em

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ils you’re sending.

And that’s why email is like cross-pollination by bees

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Not all Business Service Companies should invest in advertising to promote their companies. But I thought all businesses must advertise to stay in business? Well not all of them and let me tell you why. Once you have a secured number of customers you may not wish to advertise because you cannot take anymore work or you do not want any more work.

This article gives the definition of e-waste and states the regulations on how it can be disposed. It also tells what some companies are doing to help the consumer get rid of it.

Sometimes, the reason why a product or service fails is not because it is not relevant to its consumers, but because your market may not be aware you exist. If this is the case, you might as well close shop and do something else, or allow your business to be enhanced by marketing search engine tools.

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Digg It - Internet Basics: Email is Like Cross-Pollination by Bees

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