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One of the key measurements of everything you do is how much money do

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

you make when you send out an email? One of the easiest ways to tra

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

k this is to track how much money you make on an individual email.

W

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

hat I mean is this. If I send out an email promoting a $5 product an

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

I get 200 opens, 100 click throughs, and a 10 % conversion rate, I h

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ave sold $50 in product.

Now I can send out another email promoting

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

$50 product, only get 100 opens, 50 click throughs, and a 4% convers

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ion rate, but I have sold $100 in product. Which of the emails was m

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

st profitable?

Of course the second was more profitable, although if

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

I had looked at the metrics, it would not have appeared to be so.

T

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

erefore, one of the things that I do is to keep track of how much mon

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

y I make per email.

Currently I have about 1700 unique subscribers a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

nd I make about $60 per email I send out. I try to send 2 emails a d

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

y, but it is interesting: when I send out 3, I still get the same ave

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

rage per email. Now, I do not send the 3rd email most days, because

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

fear irritating my list. Keep in mind, some people are on several a

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

utoresponders and then I send out 2 emails a day to everyone, so some

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

people might get 5 on some days anyway, so I am already pushing it.

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

Maybe I should add the 3rd email! Seriously, though, I think I am at

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

my limit – in dollars per subscriber per month, and in emails per day

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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