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99% of all ezines are not "being a reporter" on current events; that is the first and most important thing to understand.

This means that you don't have to be publishing your ezine one day before the "deadline" of when you'v

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

e decided you'll be sending it out, and going into a great tizzy over the whole thing.

Most ezines are highly topical and related to a business, a market or futher products and services of one kind or the other, and their fu

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

ction is to keep customers in touch, as well as to convert interested parties into customers.

This gives you a constantly "rolling" audience of old hands and newbies, and an ebb and flow of subscribers and unsubscribers.

Th

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

ere are certain evergreen topics in any context that you can always write about, and write about over and over again, from many different angles, and it will always be interesting and well received.

This is the key to succes

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

ful ezine publishing.

It's not so much about "news", but about enjoyable content - and that can be as old as the hills, including a 2000 year old quote from a Roman senator; if it is interesting to your target audience, it i

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

applicable, and it can become an ezine article.

With that understood, the production of an ezine can change, and it can become far more manageable.

Tip 1: Prepare a number of issues in advance so you have at least 3-6 in h

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

and and ready to go, all the time. That's what columnists do so they don't go mad and explode from the stress of constantly trying to beat deadlines.

Tip 2: An ezine does NOT need more than ONE GOOD ARTICLE, tip, suggestion

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tc. In this day and age, people do not sit around with email as though it was the Times Magazine. Too long and too much content, and they'll put it aside for later, and later never comes as you well know with your own email.

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

Tip 3: As you're the publisher, you can have a flexible schedule. Base your ezine on something manageable, weekly, bi-monthly, but be flexible within this to suit yourself and take things like public holidays, major events in

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

your market like the SuperBowl or the Olympics into consideration.

Tip 4: You can have a "news space" in your ezine which you can fill with news, or leave blank and just send out the prepared column you have already waiting

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

to go. You don't always have to have some amazing news item in every newsletter, that's way too stressful (and probably even too much for your audience!)

Tip 5: Make it as easy for yourself as possible! Don't go mad over mai

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

merging or complicated html formatting if it's a challenge - it isn't necessary. There are people having fantastically successful newslists and ezines who stalwardly send in plain text, without any bells and whistles, but th

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

e content is good and it's appreciated all around.

Tip 6: Remember your floating audience and go back to basics every third newsletter. Advanced subscribers never mind going over the basics again, and it's essential for the

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ew subscribers. So this may be YOUR ezine No. 266, but how many people were even there for the first 100?

Tip 7: If you are planning to have a commercial newsletter that carries advertisements, include advertisements right f

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

om the start and as a matter of course. It is the easiest thing to add a short advertisement for a book on http://Amazon.com with your own affiliate link in the "ad space section", even if you have only 3 subscribers at prese

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

nt. Then, it is there, and later, when you have 3 million subscribers, you can rent out a space that already exists without disturbing your recipients or changing the format.

Tip 8: On that topic, pick a format and stick wit

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

it. That makes it MUCH easier to prepare and send newsletters on a regular basis and takes the stress right out of it. Something like: Personal greeting - Advert - Article - News - Advert, for example. That way, you just nee

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

to fill in each one and that's easy. Customers also LIKE a format they can trust and it relieves THEIR stress, just the same.

To sum up: Make it easy for yourself with pre-prepared, ready to go, ready formatted ezines that

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

just need a "season's greeting" or a short topical comment to make them right up to date. Have a number of them in hand so you can take a holiday when you want to; keep it short and sweet and stick to a simple formula.

That'

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

what the professionals do and if you do the same, you'll find having a top quality, interesting email newsletter or ezine that goes out on time, a breeze.

(c) Silvia Hartmann 2006

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Boring - that's the last word we want to hear in our training evaluations! There can be many reasons why our students feel that way. A common reason for boredom and confusion is providing too much information.

If large corporations want to attract the very best possible people to work for them then they need a robust public relations strategy and that strategy must be centered in the human resource department. Often we see in major magazines, lists of the very best corporations in America to work for. Corporations fight hard to get on this list because they want the very best people.

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