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As Human Beings, we should all have the common goal of valuing the choices that will lead to enhancement of our Personal lives, our Communities and our Earth. In order for our

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

Environment to be Healthy, the People within it must also be Healthy. We do this by becoming aware of the products that we use in our day to day lives, by living healthier li

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

festyles and through personal development.

Us as Humans tend to exploit our Environment. The same environment that we depend on for clean air and water. If our Environment do

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

es not protect us from harmful UV rays, does not prevent the spread of disease causing organisms and control pests then how will it sustain us?

Our Ecosystem has a natural ba

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

lance which we should try to maintain. By using natural products we can reduce the amount of waste material we release into the environment. We can contribute to climate stabi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ity by simply planting more trees, which reduces Carbon Dioxide in the atmosphere and hence reducing respiratory illnesses. A cleaner environment will have less disease causin

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

g organism and hence a healthier population.

Global Warming is a major concern. Global warming describes changes in climate due to human influence and results in increased te

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

mperatures. Naturally occurring processes contribute to Global Warming. Some of these include greenhouse emission of gases like Carbon Dioxide, water vapor, ozone, volcanic em

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

issions and solar activity.

Increases in temperature can have devastating effects on us and our environment. Disease carrying organisms favor warmer temperatures, an example

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

of which is the mosquito which spreads dengue fever which can be fatal. Increase in the number of disease causing organism can lead to increase in human mortality.

Other nega

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ive effects of Global Warming are increase in sea levels and subsequent damage to coastlines, increase in intensity and extreme weather conditions which can wipe out whole com

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

munities. Glacier retreat presents a problem. Fewer crops will be produced leading to greater malnutrition, less healthy individuals and animals. Unnatural increase in greenh

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ouse gases result from industrial production by burning of coal, oil and natural gas. Many Environmental groups are advocating for action against Global Warming on the Consum

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

er level. We can do our part by equipping our houses with environmentally friendly products and saving money at the same time through our purchases and changing lifestyles.

W

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e need to be aware that their are Companies that also value our Environment, are aggressively promoting products that contribute to Healthy Lifestyles. Gaiam, pronounced Guy-U

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

, is one such Company. They are not only merchants for Health and fitness related products and services, but also are involved with conservation programs that so far have resu

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

lted in the planting of 52,000 trees which of course will increase absorption of Carbon Dioxide.

Gaiam’s products reflect Gaiam’s commitment to ensuring that our World is Hea

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

lthier because we are utilizing eco-friendly products and Gaiam is delivering services that ensure our personal development. In addition to media, Gaiam’s products include mi

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

nd-body fitness and wellness solutions, organic cotton apparel and home textiles, and renewable energy solutions.

Let us renew our commitment to making ourselves both Healthy

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

in mind and body and helping to preserve our home by using eco- friendly products.We might seem insignificant in the big picture, but our contributions will eventually add up

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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