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On that note, I realize that if you are getting 100s of daily em

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ails from subscribers, you get to the point you can no longer of

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

er that personal service. At the time of this writing, I have a

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

out 6000 active subscribers who spend over $11,000 per month wit

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

h me, and I find I can answer all my email in about ? an hour a

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ay. As my list grows, and the time it takes me to answer emails

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

personally goes up, I will inevitably be forced to go to a ticke

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

t system. But I encourage you to answer emails personally as lo

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

g as you can reasonably do it.

Another thing I like to do, espe

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ially if I send out an ‘I need your help’ email to my entire lis

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

, is to answer the emails in a group email. I find that many of

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

the questions people ask will pertain to many others on my list

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

so I will simply reprint the questions, and answer several ques

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ions at one time, and send that email to my entire list.

I thin

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

k that this creates a feeling of community. Even those who have

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

not asked me questions can feel as though they are involved in t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

is conversation. They can feel included, and they will feel as

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

though I have a responsive list – one that interacts with me – s

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

why shouldn’t they?

You have to do whatever it takes to improv

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

your response rates – and you have to test and track to do that

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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It is important for Security Companies to give great customer service because the competition is often fierce in the industry. If the businesses hiring the security company do not feel they are getting good service then you can expect they will be much more open to the next security company sales person who offers a slightly lower price for the same basic purported services.

Due to the over regulation in the Franchising Industry and the litigation it is important to keep impeccable records. From the first phone call, email to the signing of the franchise agreement everything should be documented. Below is a checklist we created for our franchise company and one I wish you would consider when creating your own.

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