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Have you ever noticed how many irrelevant websites you find when you do a search these days. You might get a result that

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

says something like "Top 10 Sites on Your Search Query. The resulting page will have several different links to

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

pages that vaguely resemble your search. So, essentially you are getting a search page after your initial search just so

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the owner of that website can get a piece of the Google pie. While it is marketing genius on Google's end, it is a pain f

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

r both the Adwords advertiser and the user attempting the search.

A few months ago this wasn't that big of a prob

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

lem. Only a few entrepreneurs were innovative enough to come up with these "junk" websites with little to no useful conte

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

nt, chock full of Adsense and other ads. Unfortunately, now, several "get rich quick" schemes have promoted and guided us

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rs to make their own money on the web for doing practically nothing. The result is a complete mess. One unethical entrep

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

reneur boasted that he maintains 75000 junk sites to generate $10,000 a month in Adsense revenue. As if the internet was

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

not cluttered enough.

What Google had originally intended to be a benefit to Adwords advertisers, such as myself,

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

is actually creating competition for the same Adwords advertisers. That's right, Adwords advertisers are in competition w

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

ith the Adsense advertisers. For example, say I sell Widgets. I want to pay a maximum of $.50 per click. Someone does a

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

search for Widgets and clicks on an ad that says something like, "Don't Buy Widgets Unless You See This." Most users wou

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ld be intrigued enough to click on it even if it is towards the bottom. This junk site probably pays $.10 for this click.

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

The resulting page would have my ad displayed on there for the full price of $.50, netting them a $.15 profit (Google kee

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ps about half). So, essentially, having more advertisers for a certain keyword drives the cost per click of that keyword

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

higher and higher, so in reality, I am competing with myself to pay someone who doesn't want to work for a living.

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

Fortunately, there is some recourse. Google does give advertisers the option to opt out of the "Content Network" which i

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

s where these Adsense ads are displayed. The only problem with that is my competitors would have to opt out too, otherwis

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

e I am losing potential customers. Until Google disciplines these junk site advertisers, this problem will only get worse

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Printing actually has a lot of overhead to keep in consideration. The printing machines and other pre-press equipment alone are a big investment.

You may know that Pyramid Schemes are illegal, so you stay away from them. But what is a disguised pyramid scheme? And if you get involved in one, is it really so bad? The answer is yes, the odds are stacked against you.

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