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Before I identify who should be considering setting up a subscription website, it would be a good idea to define exactly what

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

a subscription website is.

There are two inter-changeable terms; a subscription website and membership website. Most people d

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

n't differentiate between the two.

A subscription or membership website is a site which has a password protected member area.

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

Visitors to the site have to register their details and usually make a payment before being issued with a password. The passwo

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

rd gives them access to a member-only content. The content is usually text articles, but it can be applications, digital downl

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ads or streamed video and audio clips.

In the traditional print world the subscription website can be compared to a specialis

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

newsletter or magazine. But the internet has some major advantages over print. There are almost zero distribution costs, they

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

can attract a global audience, they can be run from anywhere in the world, content can be archived in a searchable format and

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

most importantly members are able to interact with one another creating a strong sense of community.

These advantages open up

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

subscription websites to a huge number of individuals and organisations who otherwise would not be able to cost effectively se

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

l subscriptions and distribute their information. A site with as few as 500 members can provide a good income for the editor.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Examples of individuals and groups who should consider the online subscription website opportunity are:

• Authors

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

Publishers

• Consultants

• Celebrities

• Marketing Experts

• Musicians

• Hobbyis

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

s

• Public Speakers

• Personal Coaches

• Sports Coaches

• Business Owners

• Prog

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ram and Course Developers

• Teachers/ Trainers

• Directors/Producers

• Talent Agents

• Fan

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Clubs

• Associations/Societies

• Songwriters

• Writers/Journalists/Editors

• Church Gro

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ps

• Sports Clubs

• Charities

• Alumni Associations

If you consider that there are ove

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

r 50 million active blogs on the internet, many of these have a strong and loyal followings......... but they are making very

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ittle money from advertising. These are ideal candidates to convert to a subscription website so that they can start earning a

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

proper living from their expertise.

Remember everybody has knowledge and expertise that is valuable to somebody.

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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