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Although there are some varying opinions, the most common definition of RSS is that it stands for Really Simple Syndication. An RSS PODCast feed may be dynamically generated, but it appears to the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

subscriber (or consumer or user) of the feed as a file that is retrieved. Typically it is retrieved from a web server, but if you have an RSS feed file on your hard disk, you can open it. Or you

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

could make your own and open it! An RSS feed, whether PODCast or other, is just a list of files. The files in the list usually contain audio, video, photos or other images. So, to summarize, an RS

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

feed is a file that contains a list of files. This list of files represents audio files, pictures, videos, images, or other data files. The files are sometimes referred to as episodes or programs

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

if the feed is related to something delivered on a regular basis.

So what's all the fuss? And why does it seem to be so complicated? Well the list inside the file is in a special format or langu

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ge called XML, or eXtensible Markup Language. Yes another TLA ... three letter acronym. XML provides rules for putting data in a file so that the parts of the file can be easily identified. You "m

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

arkup" the data by surrounding the data elements in the file with special markers and software, called an XML parser, is able to locate and navigate through the data in an easy way (well easy for

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

rogrammers). The "markers" are the < and > symbols surrounding an the name of an element. Sometimes this is referred to as a tag. There is a tag for beginning a data item and a tag for ending. So

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

inside an XML file you might find a "title" that looks like this:

If you know how web pages work, then you know they use the HyperText Markup Language (HTML) and inside they also have tags like t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

is. The ancestry of HTML and XML is much the same so this is not surprising. However, HTML has a fixed or defined set of tags, whereas XML lets you make up your own!

Make up your own? How does an

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ybody ever agree on anything then? Well I'm glad you asked! XML also has the capability of checking the tags you have used in XML file against a list of allowed tags, called a schema. Interesting

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

enough, this list of allowed tags is also in XML! This process is called validation and an XML parser or XML validator is used for this. There are web pages where you can validate RSS feeds. So if

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

you make a schema (or XML file) of tags and enough people agree with you and start using it, you can exchange data in a common, easily verifiable format. That is exactly what RSS is. RSS is a sche

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ma for an XML file. The schema includes the tag names that were made up to hold the information such as the title and author of the RSS feed, and then there is a section for each file in the feed

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hat has the name, title, location, length, description, date created, and author.

RSS newsreaders, RSS aggregators, iTunes, and many other programs can get an RSS feed and use the RSS schema to v

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

alidate it, then retrieve the files in the list to your program to listen or view or whatever!

If you want to subscribe to an RSS PODCast Feed with iTunes or see the Technical Specification for R

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

S come on over to my website shown below.

There are picky rules about making XML files and further rules regarding the RSS schema. But if you follow the rules you can use any old text editor to c

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

reate an RSS Feed for your own files that you can use locally. If you want to make an RSS Feed available to web surfers over the Internet, you will have to make sure to put the RSS Feed file on a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

eb server AND make sure the files referenced in your RSS Feed are available via a web server as well.

As an alternative you can use a web page I created that will help you genera

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

te a valid RSS Feed that will display in your browser. Then you can view the source and copy it to use on your local disk or save and upload to web server.

Comments? Suggestions? Other cool tools

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
<a href="http://www.diggit.org.ua/article/74623/diggit-What-is-an-RSS-PODCast-Feed-and-How-Do-I-Use-It-More-Than-You-Ever-Wanted-To-Know.html">What is an RSS PODCast Feed and How Do I Use It? (More Than You Ever Wanted To Know)</a>

BB link (for phorums):
[url=http://www.diggit.org.ua/article/74623/diggit-What-is-an-RSS-PODCast-Feed-and-How-Do-I-Use-It-More-Than-You-Ever-Wanted-To-Know.html]What is an RSS PODCast Feed and How Do I Use It? (More Than You Ever Wanted To Know)[/url]

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When it comes to e-commerce, the time-tested clich? is, “Content is king.” In this case, the clich? is correct.

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