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As long as Search Engines are around, people have made every effort to get their website on top of the results. The race of being number one on google is still on and now known under the name - Search Engine Optimisation (SEO). But as much as we want to know how to get th

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ere - the more Search Engine developers try to hide the big secrets. It has become a real “cat & mouse” hunt.

People have tried many things to win this game. Some of them "good" - some "bad". Hang on, you may think, if there is a way to get my business up to the top and

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

increase my sales - I don't care how I get there! NO - that's a very plain and shortsighted assumption and would only work for a short time, if at all! The consequences are disastrous. The following Search Engine Strategies can and will put you on the search engine's "bla

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

cklists" which in simple terms mean - you are out! Banned from Google, Yahoo... and such like.

The commonly used term for bad SEO techniques is “Black Hat” SEO in contrast to “White Hat” SEO techniques which use an ethical ways to optimise a website in order to achieve b

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

tter ranking positions. Watch out which methods SEO companies are using, promising your business immediate number 1# results. This article will help you to understand the various "bad" methods, so called "Black Hat" techniques - and yes maybe there is a little bit of magi

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

c involved.

Let us put the "black hat" SEO into two categories: Content Spam and Link Spam.

Content Spam: The first search engines were using only the website’s content to measure the site's relevance to certain search keywords.

Hidden & Invisible text: This is the eas

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

iest and the most common spamming method. It simply means to set text in the same colour as the background, use a tiny font size or hide it in HTML code sections. For a real person looking at the website nothing will change, but for a search engine crawler, it will make a

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

difference. The code will have more content and so it will find a higher keyword density. This problem was quickly fixed with an algorithms to check the accessibility of the text before the search engine consider it as relevant content and then take the appropriate action

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

s.

Keyword stuffing: This can be a “black hat” method, but is also used for “White Hat” SEO.

A website can be penalised when its overloaded with a specific sentence/keyphrase in order to make a search engine think the content is more relevant than others. This technique

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

can be used in combination with hidden text too. Most of the search engines now have mechanisms in place to avoid the abuse of keywords.

Scraper sites: Web scrapping is copying content from one or more other/unrelated websites and put it on this 3rd party website withou

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

copyright permission, it's a mirror site adding no new value. Most of these websites are overloaded with advertising - which is their source of income. One should be careful to use this method, as it is severely punished.

Doorway pages: A doorway page is a fake page tha

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

t a real user will never see. It has been created to optimise search engine results, but if you click on the link, a redirect will lead you to a different webpage.

Cloaking: Basically, cloaking is quite similar to doorway pages. The difference is that the website will sh

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ow a different content depending on the IP address the user requesting the page has. If an IP address is recognised as a search engine spider, a script will deliver a different version of the page.

Link Spam: Search engines have step-by-step changed their search algorith

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

m judging the value of a website and therefore the websites ranking. Incoming links are only one attribute checked by the search engines. The more relevant the referring websites are, the better.

Link farms: On these community-like websites each member is linking to the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

thers, trying to pretend high relevance to the search engine crawler. These communities were commonly named “mutual admiration societies”.

Hidden links: The technique is the same as it is with the hidden text: Links are added to a site which visitors won’t see in order t

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

o increase their link popularity.

Sybil attack: The principle again is the same as with link farms. One person will buy multiple domain names and then create various websites linking to each other in order to pretend high value of content and importance.

Wiki Spam: A wi

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

ki is a website that everyone can edit and modify. Black Hat SEO will use it to add links to their website, most of the time on unrelated pages.

Blog Spam: As on wikis, people can add comments on blogs, forums or guest books. Posting links to a website is an easy way to

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ncrease your link popularity.

Page hijacking: This is one of the most unethical ways to increase your website's link popularity. It simply means to copy the content of another website but modifying the out-coming links. It is often referred to as 302 forwarding.

Always

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

keep in mind that the techniques mentioned above truly are unethical ways to optimise your website for search engines. Using "Black Hat" SEO can and will add your website to the blacklist of most search engines, and has the opposite effect. And it does not stop for big co

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

mpanies either many have already tried to use "Black Hat" SEO techniques and were banned. Imagine - people who will type in a banned brand name or keywords related to it and they will simply not find the website and end up on your competitors website enjoying their offers

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

HTTP = HTML link (for blogs, profiles,phorums):
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BB link (for phorums):
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Next time you're thinking about contacting the media with that freshly written press release about version 15.4 of your software, stop and think for a minute if it's what their readers want to read.

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