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This article offers some general background information on some well-known Swedish brand names, although some of them may not be commonly recognised as originally Swedish. Sweden is quite unusual in

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

that, for the size of the country, it has a relatively large number of world-class companies. Until recently, these were largely Swedish owned, and several still are, but some are now owned, wholly

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

r partly, by non-Swedish groups but are still seen as Swedish. However, most of these companies are not familiar to the majority of people because they sell to other industries and not to the general

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

public.

People working in those industries will readily recognise such names as Alfa Laval (separators, heat transfer and fluid handling systems), Aga (industrial gases - now part of the Linde Group

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

, Atlas Copco (compressors, mining and construction equipment), ASEA (electrical equipment - now part of ABB), SKF (world number 1 in ball and roller bearings and seals), SCA (pulp and newsprint, pac

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

aging, hygiene products), Sandvik (special steels and high quality tools), Stora - originally the Great Copper Mountain mining company and now part of Stora Enso (world number 1 in paper, packaging a

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

d forest products) and Ericsson (telecommunications).

However, there are also some industrial names that are recognizable to the public at large. In no particular order, these include:

Volvo 'Volv

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

’ means ‘I roll’ in Latin, and its familiar logo is based on the symbol for iron to illustrate the company’s early links with the Swedish steel industry. The general public recognizes Volvo primari

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

y as a make of cars, and the first Volvo car was built as long ago as 1927. Today, however, the car division – Volvo Car – has been spun off as a separate entity, purchased by Ford and now forms part

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

of Ford’s Premier Car Division (along with the UK’s Jaguar, Land Rover and Aston Martin and the American Lincoln). The Volvo Group now has no car-making operations and focuses on making heavy truck

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

(it is number 2 in the world behind DaimlerChrysler and owns Renault Trucks in France and Mack Trucks in the US), buses (where it is also world number 2), construction equipment (graders, excavators

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

backhoe loaders, etc) and aero-engine components. An additional and well-known division of the Volvo Group is Volvo Penta, which makes power units for leisure boats, workboats, industrial equipment,

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

etc. For more information about the Volvo Group, visit their website at http://www.volvo.com/group/global/en-gb

SAAB The name is an acronym formed from the initials of Svenska Aeroplan AktieBolag

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Swedish Aircraft Company) and the company was formed to develop a Swedish domestic military aviation industry. The company later began building cars, but SAAB Automobile was devolved in 1990 into a

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

separate entity and bought by General Motors in 2000. For many years, SAAB also made heavy trucks through its subsidiary SAAB-Scania, but Scania was also spun off as a separate company in 1995 (see b

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

low) . The SAAB Group now focuses on aviation, weapons systems, electronics and other systems and represents the major part of the Swedish defence industry. If you are interested, have a look at h

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

tp://www.saabgroup.com/en/index.htm

Scania

Scania was formed in 1891 and since then has delivered more than 1,000,000 vehicles. It merged with SAAB in 1969, but was spun off as a separate company i

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

1995 when SAAB ceased making both cars and trucks. The company is the world’s third largest manufacturer of both heavy trucks and buses and, like Volvo, heavy vehicles carrying its logo are a common

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

sight on British roads. At the time of writing, the German MAN Group is attempting to take over or merge with Scania, which would create a truck and bus group larger than Volvo and second in the worl

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

. Volksvagen, which is the largest single shareholder in both groups, has blocked a hostile bid, but is believed to favour a negotiated merger. To read more about Scania, go to http://www.scania.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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