Over the years, our keyword selection process has become quite refined. Looking over the research we've done in years past, most is good, but doesn’t live up to the 5-phase keyword research and selection process my company uses today. The first and most import

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ant step in our research process is to identify the site's major core terms. If you've read through the previous series of articles linked above you'll note that our process has evolved slightly since then. Identifying core terms (what we called “keyword theme

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s”) used to come later in our research process but we've found that by knowing all the main and/or relevant core terms, you’re better able to find all the most important phrases.

As you identify your main core terms, keep in mind that you are looking for uniq

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e two- or three-word combinations, not actual search phrases. For example "tahoe wedding" might be the core term which will cover numerous phrases including "lake tahoe wedding". Similarly "vow renewal" covers "wedding vow renewal" phrases, "wedding favors" co

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

vers "wedding shower favors" and so on. Usually we'll combine plural and singular variations into a single core term but sometimes we'll separate them, depending on the circumstance.

We begin by pouring through the site, scanning title tags, keyword tags, des

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

cription tags, text, navigation links, products, etc. By doing this thoroughly you'll be able to identify all of the main site core terms which have already been established. Looking through products and product descriptions will produce a gold mine of core te

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ms. Keep in mind that we are looking for unique two- or three-word phrases. If you're looking at motorcycle battery products, for example, you might pull 'motorcycle battery' as your obvious main core term, but you’ll also find that 'honda battery', 'solar bat

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

tery' and '12v battery' fit under the 'motorcycle battery' core term. These also will produce a number of unique phrases you can target that don't necessarily contain the word 'motorcycle.’ During the course of your in-depth research finding actual searched ph

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

rases, many keywords will overlap across multiple core terms. You're better off duplicating than you are missing any.

Once you've worked through your site, do the same with a competitor's website. Perhaps they have used a unique word combination you hadn't th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

ught of. After that it's time to jump to a few tools to dig up even more core terms. I've heard good things about Keyword Discovery but as of yet I have not had a chance to try it out. I continue to

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

use (and love) WordTracker, especially their new Keyword Researcher tool which they have been developing. I've offered a few suggested improvements so far and a few of them have already been implemented.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Useful in developing my core terms, Wordtracker has a related keywords search tool. Type anything in here and the results produced below are other phrases that may (or may not) be relevant. Pick through those results and document any new core terms found that

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

re not already on your list. Google and Yahoo both have tools which will provide similar information allowing you to find such core terms, and I also use L3xicon.com quite extensively.

Running a keyword sear

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ch through L3xicon provides results showing related words, definitions and even related web pages. It's the related words we are most concerned about, and these results come in two sections, both can provide useful information

Running a search for "tahoe wedd

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ing" L3xicon produces some results that allow us to find some additional core terms that may not have already been added to our list:

wedding chapel, wedding package, wedding planner, wedding ceremony, wedding service, wedding planner/planning

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ckquote>

These may have already been discovered when pouring through the site and through competitor's sites, but perhaps not. Next we're going to try 'outdoor wedding', a phrase that probably came up in our WordTracker search. Here a few more relevant core t

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

erms pulled from the results:

garden wedding, wedding location

Now let's click on the 'garden wedding' link provided and see the results. Look! Another core term we can use:

beach wedding

Let's try going ba

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ck and searching for 'wedding location'. From this list of results we are able to pull:

unique wedding, romantic wedding, exotic wedding, destination wedding,

And the searches can continue until you have finally found what you belie

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e to be a complete list. What then do we do with this list? We send it to our clients for review to ensure that we have not included core term that are not relevant. For example our client in Tahoe may not provide any type of garden themed weddings so they'll

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

let us know that this phrase is not relevant to their business. After that you can begin the more in-depth research of finding all the related and actively searched phrases for each of these core terms, another time-consuming but rewarding task in the long-run

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products