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Q. My boyfriend is addicted to Internet chatting. What can I do?
(Marlene)

A. Your boy

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

friend is obviously bored, either in his life or in his relationship, and is seeking company online. He i

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s not necessarily addicted. It could be that you are not talking about the things he enjoys and so he tak

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

es refuge on chat. Or that he needs extra stimulation in conversation and likes chat rooms. Either way, y

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

u are not getting the attention and he is neglecting his relationship.

There are a few things you could

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

do:
1. Join a chat room too and play him at his own game. Send him instant messages and things like

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

that. It could give your conversations a new dimension and make them more interesting.

2. Let him know

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ow you feel about it and ask him how HE would feel if most of your time was being taken up that way. Then

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ask if there are other things you could both be doing together.

3. Compromise on the time he could spen

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

d online, as long as there is equal time spent with you. So he could have a couple hours each day chattin

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

, perhaps, so long as you both share similar time together.

4. Tell him that you feel excluded from his

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

company as he seem to have no time for you. If that continues, you will have to leave him to it, and see

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

what he does.

Do bear in mind, though, that no one person can ever fulfil all aspects of our lives. We w

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

ill always be seeking stimulation outside in one form or another. The main thing is to ensure balance in

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

hatever you do. The Internet is also a novelty to many people. Sometimes the answer is simply to let it r

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

ide for a while until the novelty wears off, while you go out with friends, or find something equally int

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

eresting to do, rather than sitting around watching him. If you merely point out what he is doing, or nag

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

him about it, he will get resentful and just keep doing it.

The more we get on with our life, the more a

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ttractive we seem to others, because they have to make the running to us! So, if all else fails, find a h

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

obby too, or someone who will give you the attention you deserve and see the rapid change in his reaction

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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