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Digg It - Stopping Spam - A Useful Analogy To Understand How Email Works
I heard it dozens of times each day "I don't really know computers" or "I'm not good with computers" or "I don't speak computer", and every time it was the signal for me to step out of the wo
According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
rld of jargon and tech speak, and into the world of analogy and simplification. Generally when you simplify something you leave yourself open to massive misunderstandings down the track, esp
; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.
Examples of combination products may in
Examples of combination products may in
ecially something as complex as the workings of the internet. However there was one analogy which everyone could understand and which, when it came right down to it, goes a long way to expla
lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.
ining how email works, and as such gives us insight into the development of spam.
Consider a regular letter. At it's very simplest I write something on a piece of paper and give it to you.
Consider a regular letter. At it's very simplest I write something on a piece of paper and give it to you.
here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
But suppose you aren't next door, suppose you are at work. I can't go to your work, so I give it to someone heading that direction and they drop it off to you. Somewhere back in the darknes
d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.
Combination pro
Combination pro
s of history this happened and mail was born. The progression is simple and natural - after a while rather than giving the letter to a person who happens to be going in the correct direction
ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
someone takes it upon themselves to take all mail going in that direction. Then they take all mail going anywhere, sort it by destination and send each package in the correct direction to b
easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
e distributed when it gets to a sorting center at the destination. Then these networks of mail carriers start to work together and you have a whole big mishmash of mail flowing seamlessly th
nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
ough the system - dropped off at designated points and delivered to a pick-up point(this was once the post office, now it is your door). And that's basically how mail works, and how it evolv
and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
ed to work.
Now in the cyber age we have email, and the evolution of email is not too dissimilar to regular mail. E-messages started as an internal form of communication, then reached acros
Now in the cyber age we have email, and the evolution of email is not too dissimilar to regular mail. E-messages started as an internal form of communication, then reached acros
ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
s networks, and finally reached across the world. The system it uses is basically the same as snail mail. When you send a message it goes to your ISP. Your ISP is basically your local post
ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.
Following aspects would a
Following aspects would a
office. Your ISP looks at the address you put on your mail and sends it off in the right direction to get there. Eventually it will end up at your recipients ISP for picking up. Think of
dd to the challenges in developing combination products:
Which markets to tap where the combination products can do fairly well?
Which combination prod
Which markets to tap where the combination products can do fairly well?
Which combination prod
our recipients ISP as the post office at the other end of the chain - the one charged with getting the letter from the post office to your letterbox. When your recipient next logs in they wi
cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin
ll ask their ISP if they have new mail, and be handed your letter.
The big difference between snail mail and e-mail is SPEED. When you send an email it zaps around the world in almost no ti
The big difference between snail mail and e-mail is SPEED. When you send an email it zaps around the world in almost no ti
tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
What would be the developing cost?
How to tackle the risks encountered during combination product developmen
me at all. And here is where spam is born. The 'post offices' can screen out known spammers, and actually remove a mountain of spam before anyone ever sees it. However, spammers move fast.
t?
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
Considering that email is delivered almost instantly even the most efficient of ISP spam filters will NEVER catch the first spam mailing based purely on where it is coming from. Invariably
ping new procedures for reviewing their safety, efficacy and quality.
Professional from academic institutions, pharmaceutical industries, health care indust
Professional from academic institutions, pharmaceutical industries, health care indust
the first mailing goes through, the ISP receives a pile of complaints(these are often generated internally from their own monitoring systems) and the senders IP is investigated and banned.
T
T
y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
he other big difference between regular mail and email is cost. There is a certain amount of cost involved with setting up an internet connection, but once this is established a spammer can
.
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
quickly send out messages, and one message is as free as one thousand. With regular mail there is both a production cost and a distribution cost that scales according to volume.
The similar
The similar
elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.
Companies that provide selfless information through particip
Companies that provide selfless information through particip
ities and differences outlined in this article should give a good overview of how spam spreads so quickly, how hard it is to fight and why it does not affect the regular mail system so easily
tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products
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